Biopharmaceutics in silico modeler

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Pharmaceutical Product R&D

Job Category:

Scientific/Technology

All Job Posting Locations:

Beerse, Antwerp, Belgium

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work in teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

 

We are searching for the best talent for a Biopharmaceutics in silico modeler to be located in Beerse, Belgium.

 

Purpose:

Johnson & Johnson Innovative Medicines seeks to bring innovative and effective treatments in four therapeutic areas of high unmet medical need (oncology, immunology, neuroscience, cardiopulmonary). The Janssen campus in Beerse, close to Antwerp, (Belgium) has a unique ecosystem covering the complete drug development life cycle, with all capabilities from basic science to market access on one campus.

The biopharmaceutics group is part of Pharmaceutical & Material Sciences in Pharmaceutical Product Development & Supply. The group supports the drug product design process for both early and late development projects (for synthetic molecules) by characterizing and optimizing the link between the physicochemical properties of the active ingredient, drug product and its in vivo behavior.

 

You will be responsible for:

• Building and applying computational models to:

  • characterize the interface between the drug product and the physiological target (for multiple delivery routes)

  • predict drug absorption and disposition based upon physiological, physicochemical and in vitro release input data (eg via Physiology Based Biopharmaceutical and/or Pharmacokinetics modeling)

• Supporting the selection of the appropriate patient-centric drug delivery system and route of administration to assure optimal delivery of the active ingredient at the site of action

• Actively cooperating with external partners including academic and private research organizations to stay at the forefront of emerging scientific, industrial, and regulatory standards in the field of biopharmaceutics

• Building and demonstrating strong partnerships with key stakeholders including Discovery Sciences, Preclinical DMPK, Non-Clinical Safety, Clinical Pharmacology, Regulatory Affairs, API Development, Drug Product Development and Analytical Development

Qualifications / Requirements:

• Master or Doctorate (Ph.D.) in Pharmaceutical Sciences, Chemistry, Biology, Engineering or related science preferably with relevant industrial experience (> 2 years) in biopharmaceutics and computational modeling (drug absorption and disposition).

• Knowledge in (some of) of the following fields is recommended: physico-chemistry, drug absorption/disposition, formulation development/design, pharmacokinetics

• Scientific specialist via a single contributor role, with excellent interpersonal, communication and collaborative skills, while demonstrating a high degree of personal accountability.

 

 

Required Skills:

 

 

Preferred Skills:

Coaching, Collaborating, Critical Thinking, Drug Discovery Development, Goal Attainment, Market Research, Organizing, Pharmaceutical Sciences, Pharmaceutical Trends, Product Development, Product Strategies, Report Writing, Research Documents, Research Proposals, Scientific Research, Standard Scientific Processes and Procedures, Technologically Savvy