Application Support Engineer

Job Description

We are seeking a mid-level Application Support Engineer to support the expansion of our Global Application Support on-site in Indianapolis, IN. This role is ideal for an engineer with strong SQL and application troubleshooting experience, who can independently support production applications, analyze data issues, and partner with global teams to ensure system reliability in a regulated pharmaceutical environment.

Key Responsibilities

• Provide Tier 2 / Tier 3 application support for critical manufacturing and enterprise applications, including incident response, troubleshooting, and root cause analysis


• Use SQL to analyze application data, investigate issues, validate fixes, and support reporting or data corrections as needed


• Serve as a technical escalation point for complex application and data-related issues, coordinating with global support teams, developers, and vendors


• Support application lifecycle activities, including deployments, upgrades, patches, and validation support in GxP-regulated environments


• Partner with business users, IT, and engineering teams to identify recurring issues, propose improvements, and enhance application performance and stability


• Create and maintain support documentation, SOPs, runbooks, and knowledge base articles


• Ensure compliance with GxP, data integrity, change management, and cybersecurity requirements

Additional Information

Required Qualifications

• Bachelor’s degree in Engineering, Computer Science, Information Systems, or a related technical field (or equivalent experience)


• 3–6 years of experience in application support, systems support, or manufacturing IT


• Strong hands-on experience with SQL (querying, troubleshooting data issues, performance analysis)


• Experience supporting applications in pharmaceutical, biotech, or other regulated manufacturing environments


• Familiarity with incident, problem, and change management processes (ITIL or similar)


• Strong communication skills and ability to work effectively in an on-site, cross-functional environment

Preferred Qualifications

• Experience supporting manufacturing execution, quality, Data Historization and/or laboratory systems


• Knowledge of GxP validation, audit support, and regulated change control


• Experience working with SQL Server, Oracle, or similar relational databases


• Exposure to global application support models and follow-the-sun operations

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