Director, Clinical Trial Finance

About Us: 

Structure Therapeutics develops life‐changing medicines for patients using advanced structure‐based and computational drug discovery technology. The company’s platform combines the latest advancements in visualization of molecular interactions, computational chemistry, and data integration to design orally available, superior small molecule medicines that overcome current limitations of biologic and peptide drugs. We are advancing a clinical‐stage pipeline of differentiated treatments focused on chronic diseases with high unmet need, including cardiovascular, metabolic, and pulmonary conditions. 

Structure Therapeutics is led by an experienced group of international drug innovators and financed by top-tier global life sciences investors. The company completed an initial public offering (IPO) in February 2023. With offices in California and Shanghai, Structure Therapeutics has the benefit of being at the center of life science innovation in both the US and China and capitalizing on the strengths of each geographic location. Reporting directly or operationally into the VP, Clinical Operations, the role supports the broader coordination of efforts across teams to ensure impactful contributions to AI integration 

Position Summary:

The Director, Clinical Trial Finance will lead financial planning and oversight of clinical trial activities, including accruals, in support of the company’s development portfolio. Reporting to the Executive Director, FP&A, this role serves as a key strategic partner to Clinical Operations, Development, FP&A, and Accounting, ensuring strong financial governance, accurate reporting, and actionable insights to inform decision-making.

The ideal candidate brings deep expertise in biotech finance, a thorough understanding of clinical development, and a strategic, hands-on approach to driving financial performance in a dynamic, growth-oriented environment.

This is an opportunity to play a critical role in advancing a global, publicly traded biotech company’s pipeline and supporting the successful execution of clinical programs.

Job Responsibilities:

• Lead, mentor, and scale the Clinical Trial Finance function, including direct management of the Senior Clinical Trial Finance Manager.


• Drive financial planning, budgeting, forecasting, and long-range planning for clinical trials; oversee financial management across programs, including accruals and variance analysis, in alignment with corporate objectives.


• Oversee financial management of clinical trial contracts, amendments, and compliance with financial terms.


• Partner closely with Accounting to ensure accurate and timely financial close processes, including journal entries, reconciliations, and reporting of clinical trial costs.


• Serve as the primary finance business partner to Clinical Operations, Development, and Program Management, providing insights and ad hoc financial reporting to support decision-making.


• Establish and maintain strong relationships with Contract Research Organizations (CROs), vendors, and external partners.


• Lead audit readiness efforts and support internal and external audits related to clinical trial expenditures.


• Continuously enhance financial processes, systems, and internal controls to support scalability and operational excellence.

Qualifications:

Experience

• 10+ years of finance experience, including 7+ years in increasingly responsible roles within finance and accounting, with significant experience supporting clinical trials in the biotech or pharmaceutical industry.


• Deep industry experience with strong understanding of clinical development, industry dynamics, and key financial drivers.


• Strong knowledge of GAAP and SOX compliance, with deep expertise in accrual accounting and clinical trial financial management, including contracts and CRO oversight.


• Proven leadership experience with a track record of building and developing high-performing teams.


• Advanced financial modeling and forecasting capabilities, including scenario planning and analysis.


• Strong analytical, strategic thinking, and problem-solving skills.


• Excellent communication and interpersonal skills, with the ability to influence cross-functional stakeholders and external partners.


• Proficiency in financial systems and Microsoft Office Suite.

Preferred Experience

• Experience supporting global clinical trials and managing financials across multiple currencies.


• Experience with NetSuite, Zip, and Condor preferred.


• Strong project management skills with the ability to manage multiple priorities in a fast-paced environment.

Education

• Bachelor’s degree in Finance, Accounting, or a related field required.


• CPA or MBA preferred.

Travel Required:

Occasional travel may be required based on business needs. 

Structure Therapeutics Inc. is an Equal-Opportunity Employer. 

Structure Therapeutics is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. For this role, the anticipated base pay range is $205,000 - $250,000. The exact base pay offered for this role will depend on various factors, including but not limited to the candidate’s geography, qualifications, skills, and experience. 

At Structure, base pay is only one part of your total compensation package. The successful candidate will be eligible for an annual performance incentive bonus, new hire equity, and ongoing performance-based equity. Structure Therapeutics also offers various benefits offerings, including, but not limited to, medical, dental, and vision insurance, 401k match, unlimited PTO, and a number of paid holidays including winter shutdown.  

Notice to Recruiters/Staffing Agencies 

Recruiters and staffing agencies should not contact Structure Therapeutics through this page. All recruitment vendors (search firms, recruitment agencies, and staffing companies) are prohibited from contacting our hiring manager(s), executive team members, or employees. 

We require that all recruiters and staffing agencies have a fully executed, formal written agreement on file.

Structure Therapeutics’ receipt or acceptance of an unsolicited resume submitted by a vendor organization to this website or employee does not constitute an actual or implied contract between Structure Therapeutics and such organization and will be considered unsolicited and Structure Therapeutics will not be responsible for related fees.  

Fraud Alert 

To all candidates: your personal information and online safety are a top priority for us. At Structure Therapeutics, direct candidates to apply through our official career page at BambooHR. 

Recruiters will always contact you using the domain of Structuretx.com. We will never request payments, ask for financial account information or sensitive information like social security numbers. If you are unsure if a message is from Structure Therapeutics, please email human resources.