Engagement Manager (Medical Strategy & RWE)

Who are Prescient?

Prescient is a specialist global consultancy focused exclusively on the biopharmaceutical industry. Following the recent acquisitions of Uptake and Dolon, Prescient now operates across four core practices: Commercial, Medical, Competitive Strategy and Value, Pricing & Access. Together, we deliver best-in-class intelligence, evidence and strategic consulting to leading biopharma organizations worldwide.

Our work supports clients across the full product lifecycle, from early pipeline through post-launch, delivering timely insights and strategic recommendations that enable informed decision-making across commercial, medical, competitive intelligence, evidence generation and market access function.

Within our Medical practice, we deliver integrated solutions across three core pillars - Medical Strategy & Planning, Evidence Generation Strategy, and Organizational Excellence - enabling clients to strengthen medical impact, accelerate decision-making and build future-ready medical organizations. Increasingly, our differentiation comes from pairing genuine scientific and technical depth with strategic medical affairs judgement.

About the role

As an Engagement Manager, you will lead the delivery of strategic medical affairs engagements while driving business growth and developing the teams around you. This role spans our three core pillars, medical strategy and planning, evidence generation and organizational excellence and calls for a consultant who pairs strong technical grounding in real-world evidence (RWE), health economics and outcomes research (HEOR) and epidemiology modelling with the medical affairs understanding to put that evidence to strategic use.

Our clients, medical affairs leaders at leading pharmaceutical and biotech companies, increasingly expect partners who can do more than synthesise their thinking. They want technical depth they can trust, fluency in how medical affairs operates, challenge to their assumptions, and clear answers to “so what” and “now what.” You will be central to meeting that expectation, with a primary client base in the U.S. and a global perspective on medical strategy, evidence generation, and drug development.

What role will I play on projects?

You will lead engagements end to end; scoping the approach, directing the work and owning the quality and strategic relevance of what we deliver. You will help clients address challenges across medical planning and strategy, integrated evidence generation, launch readiness, field medical optimization and operating-model design.

• Lead client engagements end to end across medical strategy, evidence generation and organizational excellence. You will oversee research, analysis and the design of deliverables such as strategic and medical plans, evidence roadmaps, operating models and client workshops.


• Bring technical depth where it matters. Direct or guide RWE study design, literature reviews and epidemiology work, applying the right level of methodological scrutiny so findings withstand expert review.


• Ground the work in medical affairs strategy. Connect evidence and analysis to clients’ medical objectives evidence-generation planning, scientific communication, field medical and launch, demonstrating a clear understanding of how medical affairs creates value.


• Own the “so what” and “now what.” Translate complex evidence and analysis into clear strategic implications and recommended actions; pressure-test interpretations and bring perspectives on what clients should do differently.


• Identify and pursue new business within existing and new clients; develop proposals, scope and cost engagements accurately and position the practice competitively at the executive level.


• Manage, mentor, and develop direct reports and project teams, setting clear expectations, building both technical and strategic capability, and reducing variability in how the team delivers.


• Manage workstreams and stakeholders, ensuring coordination, efficient communication and timely delivery against a high standard of quality.


• Contribute to the evolution of the practice by helping shape new capabilities and offerings across medical strategy, evidence generation and organizational excellence.

What skills and experience do I need for this role?

• Advanced degree strongly preferred - PhD, MD, MS/MBA combination or master’s (MS, MPH, or equivalent) in a life-sciences, epidemiology, health economics, biostatistics or related discipline.


• 5–7 years of relevant professional experience, with a strong foundation in medical affairs, evidence generation or life-sciences strategy.


• Prior consulting experience is required - a proven ability to deliver impactful client work and manage engagements in a consulting environment.


• Strong understanding of medical affairs and how evidence, scientific strategy and field medical connect to broader business priorities and patient impact across the product lifecycle.


• Ability to interrogate evidence and translate it into strategy - connecting technical findings to clinical and commercial implications without losing rigour.


• Demonstrated business development ability - building and sustaining senior client relationships and converting opportunities into growth.


• Strong leadership and people-management skills, with a track record of managing and developing teams and direct reports.


• Superior written and verbal communication, able to distil complex science and evidence into clear, credible, executive-ready narratives for cross-functional audiences.

What we offer

• A competitive package and remuneration linked to performance


• A high-growth, entrepreneurial environment where you can create significant client and business value and forge your own path


• A platform for accelerated professional development and career growth with significant levels of responsibility and accountability, and the opportunity to be part of the US management team


• An opportunity to lead extraordinary teams that are driven by personal learning and client impact

The annual full time base salary range for this role is ($140,000 - $165,000). Specific compensation is determined through interviews and a review of relevant education, experience, training, skills, geographic location and alignment with market data. Additionally, positions may be eligible to receive a discretionary bonus as determined by bonus program guidelines. Prescient offers PTO and paid holidays, the terms of which are set forth in the program policies. All full-time employees also are eligible to participate in various benefit plans, including medical, dental, vision, life, disability insurance and 401K; in each case in accordance with the terms of the applicable plans.

We are an equal opportunity employer and fully comply with applicable legislation in all of the geographies in which we operate. Applicants are considered for positions without regard to veteran status, uniformed service member status, race, color, religion, sex, national origin, age, physical or mental disability, genetic information or any other category protected by applicable national, federal, state or local laws.

Don’t meet every job requirement? That’s okay! Our company is dedicated to building a diverse, inclusive and authentic workplace. If you’re excited about this role, but your experience doesn’t perfectly fit every qualification, we encourage you to apply anyway. You may be just the right person for this role or others.