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Scientist II (Oligonucleotide Synthesis)

Job Description - Scientist II (Oligonucleotide Synthesis)

Our client, a world leader in biotechnology and life sciences, is looking for an “Scientist II (Oligonucleotide Synthesis)” based in South San Francisco, CA.

Job Duration: Long Term Contract (Possibility Of Extension)
Rate: $51/hr on W2
Company Benefits: Medical, Dental, Vision, Paid Sick leave, 401K

Overview
This role focuses on oligonucleotide therapeutics discovery, supporting RNAi-based research through synthesis, characterization, and collaboration across therapeutic areas.

Key Responsibilities
  • Design and execute oligonucleotide synthesis and purification workflows.
  • Perform HPLC and mass spectrometer analysis for characterization and impurity profiling.
  • Support RNAi and nucleic acid therapeutic discovery across neuroscience, immunology, and oncology programs.
  • Develop and scale up synthesis of lead oligonucleotide candidates for pre clinical studies.
  • Collaborate with cross-functional teams to integrate chemistry and biology data.
  • Maintain and troubleshoot lab equipment (e.g., oligo synthesizers, HPLC systems).
  • Conduct literature reviews and contribute to experimental design and strategy.
Qualifications
  • BS/MS in Organic Chemistry or related field.
  • Hands-on experience with oligonucleotide synthesis, purification, and characterization.
  • Experience with automated oligo synthesizers, HPLC, and mass spectrometry.
  • Understanding of RNAi, nucleic acid therapeutics, and modification chemistries preferred.

If interested, please send us your updated resume at [email protected]/[email protected].

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About the Company

Dawar Consulting Inc

Enabling Cloud Adoption. Leading Human Capital Management Solutions and Consulting Firm. Global Talent Acquisition & Staffing Services Provider

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