Scientist II/III, LCMS Method Development (Bioanalysis)

Position: Scientist II/III, LCMS Method Development ( Bioanalysis)

Salary Range: $65,000-$85,000

Location: Exton, PA (On-site)

About Pharmaron

Pharmaron is a global CRO (Contract Research Organization) helping pharma and biotech companies bring new therapies to life. With over 21,000 employees worldwide across 23 locations in the US, UK and China, we support drug discovery through to manufacturing with fully integrated, high-quality services.

We're proud of the impact we make and just last year, we supported over 780 discovery projects, 1,000+ CMC programs, and 1,000+ clinical trials across all phases. Our teams are involved in everything from small molecules, ADC's, biologics, and gene therapies and we work with more than 3,000 global customers. To learn more, visit www.pharmaron.com.

Job Overview:

Pharmaron is seeking a Scientist II/III, LCMS Method Development (Bioanalysis) to join our growing Bioanalytical Sciences team in Exton, PA. In this role, you will contribute to the development and validation of innovative bioanalytical methods supporting drug discovery and development programs across a diverse range of therapeutic modalities, including small molecules, peptides, oligonucleotides, PROTACs, biologics, and emerging therapies.

Key Responsibilities

• Independently develop, optimize, validate, and troubleshoot LC-MS/MS bioanalytical methods.


• Design scientifically sound studies that meet sponsor and internal objectives.


• Execute and support bioanalytical testing for DMPK and regulated studies.


• Perform sample analysis using HPLC and LC-MS/MS platforms in compliance with developmental and GLP requirements.


• Review and execute study protocols governing bioanalytical studies and sample analysis.


• Process, analyze, interpret, and report study data.


• Author protocols, validation reports, technical summaries, and study reports.


• Support regulatory submissions through high-quality scientific documentation.


• Serve as Principal Investigator (PI) and/or Study Director (SD) within areas of expertise.


• Actively identify and resolve technical challenges while driving continuous improvement.


• Collaborate with scientists, project teams, management, business development, and clients to ensure successful project execution.


• Participate in project review meetings and compliance-related initiatives.

What We're Looking For

• Bachelor's degree in Pharmaceutical Sciences, Chemistry, Life Sciences, or a related scientific discipline.


• Scientist II: Minimum 2 years of bioanalytical testing experience.


• Scientist III: Minimum 4 years of bioanalytical testing experience.


• Experience supporting development and/or GLP-regulated bioanalytical studies.


• Strong understanding of HPLC and LC-MS/MS methodologies.


• Excellent analytical thinking, troubleshooting, and organizational skills.


• Ability to thrive in a fast-paced, collaborative, and matrixed environment.

Preferred Qualifications

• Experience with LC-MS/MS method development and validation.


• Experience analyzing peptides, oligonucleotides, PROTACs, and complex biologics.


• Familiarity with DMPK studies and regulated bioanalysis.


• Experience authoring scientific reports and supporting regulatory submissions.


• Prior CRO, pharmaceutical, or biotechnology industry experience.


• Experience serving in client-facing scientific roles.

Why Pharmaron?

Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 21,000 employees and operations in the U.S., the U.K. and China. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China.

Collaborative Culture: You will thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners, and collaborators.

Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package:

• Insurance including Medical, Dental & Vision with significant employer contributions


• Employer-funded Health Reimbursement Account


• Healthcare & Dependent Care Flexible Spending Accounts


• 100% Employer-paid Employee Life and AD&D Insurance, Short- and Long-Term Disability Insurance


• 401k plan with generous employer match


• Access to an Employee Assistance Program

How to Apply:

Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today!

As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.

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