Senior Manager, Manufacturing

Repligen is seeking a detail-oriented, hands-on, and strategic Senior Manager, Manufacturing to lead and oversee all production activities within our custom plastics fabrication shop. This includes process deployment aids, fabrication of thermoplastic tanks, and various rigid accessories. This role is responsible for ensuring manufacturing processes operate efficiently, safely, and reliably while meeting quality and delivery objectives. The ideal candidate combines strong leadership, deep technical knowledge, and a track record of managing people and systems in a fast-paced manufacturing environment.

This role is expected to model our Leadership Behaviors—Integrity & Compliance, Customer Focus, Collaboration, Courage, Team Empowerment, and Accountability & Results—in all aspects of work.

• Lead and oversee daily production operations to ensure on-time, high-quality manufacturing that meets customer requirements.
• Develop, implement, and manage production plans and schedules, adjusting resources and workflows as needed to meet demand.
• Recruit, train, mentor, and develop a high-performing production team, including performance management, coaching, and succession planning.
• Monitor, analyze, and report on key performance indicators (KPIs) such as safety, quality, output, efficiency, and waste.
• Collaborate cross-functionally with Supply Chain, Maintenance, Engineering, and Quality teams to drive operational effectiveness and continuous improvement.
• Ensure compliance with safety, quality, and environmental standards, maintaining accurate production documentation.
• Drive continuous improvement initiatives using Lean, Six Sigma, and Repligen Performance System (RPS) methodologies, including leading Kaizen events.
• Identify cost-saving opportunities and implement process optimizations through technology, workflow improvements, and operational best practices.
• Partner with the Director of Manufacturing to support long-term manufacturing strategy and capacity planning.

 

 

Required:

• At least one of the following:
  • BS/BA degree in Engineering, Manufacturing, or a related field and 8+ years of related experience, or
  • Masters Degree in related field and 6+ years of experience, or
  • PhD and 3+ years of related experience.
• At least 4 years in a supervisory or management role.
• Strong knowledge of production planning, quality control principles, and health and safety regulations.
• Proven ability to interpret technical drawings, bills of materials (BOMs), and standard operating procedures (SOPs).
• Proficiency with production management software (ERP, MES, or similar systems).
• Demonstrated problem-solving skills and proactive approach to operational challenges.
• Excellent leadership, communication, and interpersonal skills.
• Strong time management skills and ability to meet deadlines consistently.
• Background in manufacturing, with experience in cabinet or furniture making, mechanical engineering, carpentry, and/or working knowledge of GD&T (Geometric Dimensioning & Tolerancing) principles.

Preferred:

• Experience in plastics or thermoplastic fabrication.
• Lean or Six Sigma certification.
• Prior experience in a fast-paced, high-mix manufacturing environment.

Our mission is to inspire advances in bioprocessing as a trusted partner in the production of biologic drugs that improve human health worldwide. Focused on cost and process efficiencies, we deliver innovative technologies and solutions that help set new standards in bioprocessing. The estimated hourly rate/salary range for this role, based in the United States of America is $126,000/yr. - $193,200/yr. Compensation decisions are dependent on several factors including, but not limited to an individual's qualifications, location, internal equity, and alignment with market data. Additionally, employees are eligible to participate in one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits such as paid time off, health/dental/vision, retirement benefits and flexible spending accounts. All compensation and benefits information will be confirmed in writing at the time of offer.