SUMMARY
Triveni Bio is in search of an innovative Sr. Research Associate to join our Biologics team. In this role, you will lead the development, optimization, and execution of cell-based assays to evaluate the potency and function of biologics within Triveni’s therapeutic pipeline. Your work will directly contribute to the validation of new treatments for inflammatory diseases. On a day-to-day basis, you will culture a wide variety of continuous cell lines and primary cells, conduct functional readouts, and analyze the resulting data to identify high-potential candidates. This is a unique opportunity to apply your expertise in cellular biology and assay development to directly impact cross-functional therapeutic development.
KEY RESPONSIBILITIES
- Design, develop, and optimize robust cell-based assays to evaluate biologics potency and mechanism of action.
- Establish, culture, bank, characterize, and maintain a wide variety of mammalian continuous cell lines and primary cells.
- Execute multiplexed and functional readouts using Flow Cytometry, ELISA, and Meso Scale Discovery (MSD) platforms.
- Analyze, interpret, and present experimental data using software tools such as GraphPad Prism, FCS Express, etc.
- Maintain rigorous documentation of experimental designs, protocols, and results in an Electronic Laboratory Notebook (ELN).
- Collaborate with cross-functional preclinical teams to advance therapeutic pipelines.
- Other duties as assigned.
QUALIFICATIONS
- Bachelor’s or Master’s degree in Cell Biology, Biochemistry, Molecular Biology, or a related field with 2+ years of relevant experience developing and troubleshooting cell-based assays for evaluating the potency and function of biologics.
- Demonstrated expertise in mammalian cell culture, specifically managing both diverse continuous cell lines and sensitive primary cells.
- Proven technical proficiency with Flow Cytometry, ELISA, and MSD assay platforms.
- Strong data analysis skills.
- Excellent organizational skills with a strict commitment to accurate ELN documentation and data integrity.
PREFERRED (But Not Required)
- Prior industry experience working specifically with therapeutic antibodies.
- Experience with monoclonal and bispecific antibodies.
- Hands-on experience with AKTA chromatography systems and proficiency in standard purification techniques such as affinity and SEC.