Biological Chemist for internship in Biocatalytic Process Research

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biological chemist for internship in biocatalytic process research

biological chemist for internship in biocatalytic process research.

beerse, antwerpen

1 dag geleden gepubliceerd

sluit 30 augustus 2023

solliciteer

jobdetails

samenvatting

beerse, antwerpen

janssen pharmaceutica

tijdelijk

38 uren per week

functiegroeptechniek

referentieDUORS-1484040

jobdetails You will be responsible for conducting research directed to developing creative solutions to
synthetic chemistry problems across a portfolio of projects. In the High Throughput
Experimentation Biocatalysis (HTE Biocatalysis) team, we focus on developing new
biocatalysts for chemoselective and enantioselective biotransformations. The ...HTE Biocatalysis team operates across a portfolio of projects focusing on the development of
biocatalytic processes for the Janssen pipeline, generating creative and innovative ways
towards new biosynthetic routes and solutions, that enable large scale
manufacturing of target active pharmaceutical ingredients (API¿s).
This is an outstanding occasion to participate in a real-life industrial research program at a
state-of-the-art facility. After an initial training provided by an experienced team member, the
successful candidate will team up with process chemistry, crystallization, engineering, and
safety experts to support the design of the best manufacturing process. These cross-functional
teams work closely together bridging the pilot plants with commercial production. New
chemical processes are developed meeting stringent requirements concerning safety,
environment, technology, economy and quality. As a result of these endeavours, drug
candidates are accelerated through the development pipeline by enabling sufficient supplies of
API¿s in support of clinical trials, registration and finally commercialization.
toon meer You will be responsible for conducting research directed to developing creative solutions to
synthetic chemistry problems across a portfolio of projects. In the High Throughput
Experimentation Biocatalysis (HTE Biocatalysis) team, we focus on developing new
biocatalysts for chemoselective and enantioselective biotransformations. The
HTE Biocatalysis team operates across a portfolio of projects focusing on the development of
biocatalytic processes for the Janssen pipeline, generating creative and innovative ways
towards new biosynthetic routes and solutions, that enable large scale
manufacturing of target active pharmaceutical ingredients (API¿s).
This is an outstanding occasion to participate in a real-life industrial research program at a
state-of-the-art facility. After an initial training provided by an experienced team member, the
successful candidate will team up with process chemistry, crystallization, engineering, and
safety experts to support the design of the best manufacturing process. These cross-functional
teams work closely together bridging the pilot plants with commercial production. New ...chemical processes are developed meeting stringent requirements concerning safety,
environment, technology, economy and quality. As a result of these endeavours, drug
candidates are accelerated through the development pipeline by enabling sufficient supplies of
API¿s in support of clinical trials, registration and finally commercialization.
toon meer

ervaring

<1 jaar

jouw aanbod

Mentored by an industry expert, you will contribute to the development of biosynthetic routes
towards organic molecules in the context of a biocatalytic process project. The goal is to
develop the best possible biocatalytic process to manufacture API¿s at commercial supply
scale by supplying novel biocatalysts through recruitment, protein engineering, and screening
campaigns. In this context, you will have the chance to improve patients¿ lives.

Responsibilities and duties:
- Work together with a group of highly motivated scientists in a pioneering laboratory in
the J&J chemistry department.
- Participate in an active small molecule drug development program.
- After an initial training and introduction in the department, able to independently
operate (under supervision) and propose alternatives or solutions for challenging
biocatalytic routes.
Qualifications:
- Strong theoretical and practical background in molecular biology, biocatalysis, and
chemistry.
- Experience with analytical techniques such as UV-Vis spectroscopy,
gel electrophoresis, LC-MS and GC.
- Highly motivated and open mindset to operate and learn in a dynamic scientific
environment, both independent and as part of a team.
- Fast learner, independent & critical thinker.

ons aanbod

We provide an allowance per worked day, to cover for your daily
expenses. Additional support for housing opportunities is available depending on the
distance to campus. By participation in trainings and events you will be able to
broaden your expertise and knowledge.
Requirement & How to apply for this position:
The candidate must be a registered student for the entire course of the internship.
Unfortunately, graduates that are currently not enrolled in a study program are not eligible for
this internship.
If you are interested in applying for this challenging internship, please send an e-mail to ra-
[email protected], including your resume and a short motivation.
Note: AN INTERNSHIP CAN ONLY START IF YOUR SCHOOL AGREES TO SIGN THE
STANDARDIZED INTERNSHIP CONTRACT OF J&J BELGIUM. We cannot accept
external contracts from the schools. Please, check this with your school BEFORE applying for
an internship position.