Associate Director, Global Health Economics and Outcomes Research

Do you excel at translating complex data into compelling value propositions for diverse stakeholders? Are you ready to lead cross-functional projects and provide strategic HEOR insights that impact rare endocrine disease treatments worldwide?

Then we have the right opportunity for you

Ascendis Pharma is a global biopharmaceutical company committed to making a meaningful difference in patients’ lives. Guided by our core values of Patients, Science, and Passion, we are applying our innovative TransCon® technology platform to fulfill our mission of developing new therapies that demonstrate best-in-class potential to address unmet medical needs.  At our headquarters in Hellerup, Denmark, research facilities in Heidelberg, Germany, and additional offices across Europe and the United States, we are advancing programs in our Endocrinology Rare Disease and Oncology portfolios. We also collaborate with partners on the development of TransCon-based products in other therapeutic areas and markets. 

The role
As the Associate Director, Global Health Economics and Outcomes Research, you will be responsible for assisting in the planning and implementation of HEOR studies to demonstrate and differentiate the value proposition and corresponding scientific evidence of Ascendis products for payers, patients, health care practitioners, and other key stakeholders. Through project leadership and collaboration with cross-functional teams, you will ensure that the global HEOR evidence generation strategy aligns with broader endocrine rare disease area development strategies. In this role, you will partner with and provide thought leadership to Market Access, Commercial teams, Regulatory, Clinical Operations, Clinical Development, and Medical Affairs.

You should be based in Denmark, the UK, Spain, or Germany, and will report to the Director of Global Health Economics and Outcomes Research, who is based in the UK.

Your key responsibilities will be

• Design and execute prospective and retrospective studies including database analyses, comparative effectiveness, meta-analyses/systematic reviews, and patient-reported outcome (PRO) studies, and economic modeling to support the value proposition
• Follow best practices for HEOR data collection, analysis, modeling, dissemination and publication
• Internal and external stakeholder collaboration in the execution of health economic and outcome research studies, including but not limited to retrospective claims analysis, prospective observational studies, patient-reported outcomes, comparative effectiveness research, network meta-analysis, and economic modeling.
• Support design and development of global economic models and local adaptations for European and International Markets.
• Thorough understanding of the field of Health Technology Assessment at a global level and experience of successful negotiations through the HTA processes
• Lead and work closely with cross-functional teams (e.g., Medical Affairs, HEOR, Market Access, Clinical Development) to develop global core-value, AMCP and reimbursement/HTA dossiers within global regions.
• Lead vendor management for the timely execution of health economics and outcomes research (HEOR) projects including but not limited to contracting, project management, and invoice approval.
• Participate in the development, review, and writing of abstracts, posters, slide presentations, and manuscripts in support of evidence dissemination strategies.
• Ability to review and summarize published HEOR literature including but not limited to economic cost analysis, patient reported outcomes, primary and secondary data analysis. This includes ability to conduct focused literature reviews and systematic reviews.
• Manage multiple projects and budgets to target as directed as well as interact with vendors in the execution of HEOR projects.
• Contribute to the development of product value propositions through product lifecycle

 Qualifications and skills

• 5+ years of HEOR experience in the pharmaceutical or a related industry
• Ability to travel up to 20% of the time domestically and internationally
• Minimum of Master’s degree required, (Ph.D. preferred) in Health Economics, Outcomes Research, Health Services Research, Public Health or related discipline.
• Experience in payer tool development and data dissemination strategy, including dossier development and reimbursement submission.
• Experience in the design and development of budget impact and cost effectiveness models.
• Expertise in the design and methodological considerations of real-world evidence studies, including administrative claims analysis, patient reported outcome data, electronic medical records and registry databases.
• Expertise and understanding of global healthcare systems and payers.

Key competencies

You are an excellent communicator with strong writing skills, able to convey complex scientific and economic information clearly and persuasively. You are a problem solver who thrives on tackling challenges and finding innovative solutions. Your strong interpersonal skills help you build effective relationships with internal and external stakeholders. You are a highly motivated self-starter, capable of managing multiple priorities independently and driving projects forward. You adapt easily to dynamic environments and excel at aligning HEOR strategies with broader organizational goals

Apply now
Applications will be evaluated when received, so please apply as soon as possible. Please note that applications received via e-mail will not taken into consideration.

If you are passionate about contributing to the field of rare diseases and eager to make a difference at Ascendis Pharma, we encourage you to apply for this exciting opportunity. Join us in our mission to advance therapeutic innovations and improve patient lives worldwide.