Medical Director, Clinical Development

Would you enjoy leading drug development for rare conditions? Are you a medic with experience designing clinical trials and interacting with regulatory authorities?

If so, now is your chance to join Ascendis Pharma as our new Medical Director, Clinical Development, Endocrine & Rare Diseases

Ascendis Pharma is a fast-growing global biopharmaceutical company committed to making a meaningful difference in patient’s lives. We have locations in Denmark, Germany, the United States, the UK, Italy, Spain, and France.

 Guided by our core values of Patients, Science, and Passion, we use our TransCon® drug development platform to fulfill our mission of developing new therapies, selecting only those that demonstrate best-in-class potential to address unmet medical needs.

Today, we are advancing programs in Endocrinology Rare Disease and Oncology. In addition, we collaborate with partners around the world on the development of TransCon-based products for other therapeutic areas and markets.

We are seeking an energetic Medical Director to join our growing team. As a key member of the Ascendis Pharma team, you will play a crucial role in driving the design, safety monitoring, and data analysis of the Company’s late-phase clinical trials studying TransCon C-type natriuretic peptide (CNP). This is an exciting opportunity to work in a fast-paced environment, collaborate with cross-functional, global teams working together to achieve extraordinary results.

You will report directly to the VP, Clinical Science, Endocrine and Rare Disease Medical Sciences.

Your key responsibilities will be

• Contribute to formulation and implementation of the Clinical Development Plan
• Leverage medical expertise and hands-on clinical experience to promote relevance and rigor of the development program
• For clinical trials: design, provide overall oversight, and support site and subject retention
• Serve as a Medical Monitor for clinical trials, ensure study integrity, and track accumulating safety and efficacy data
• Provide leadership to teams of medical monitors
• Provide leadership to study teams
• Ensure successful completion of trial-related documents (including clinical trial protocols, investigator brochures, medical monitoring plans, site training materials, clinical study reports, health authority responses, standard operating procedures, etc.) with cross-functional team members
• Ensure study integrity, and track accumulating safety and efficacy data
• Analyze, evaluate, interpret, and report clinical data
• Anticipate and solve complex drug development problems
• Contribute to regulatory strategy
• Contribute to drafting and reviewing of clinical documents, manuscripts, presentations, and regulatory submissions
• Maintain up-to-date knowledge of relevant science, medical information, good clinical practices, and regulatory guidance
• Collaborate with—and serve as a clinical research resource for—cross-functional colleagues (e.g. in clinical operations, statistics, regulatory affairs, medical affairs, health economics outcomes research, commercial, finance) to optimize product development
• Contribute to (and may be asked to represent the clinical development department in) corporate strategic and organizational initiatives
• Cultivate relationships with investigative sites, clinical consultants, and key opinion leaders to represent the interests of the company
• Assist in portfolio management and commercial activities as needed
• Complete assigned tasks thoroughly, accurately, and on time
• Adhere to rigorous ethical standards

Requirements

Qualifications and Skills:

• M.D. degree
• Ph.D. degree (strongly preferred)
• Completion of an accredited residency and fellowship (strongly preferred)
• Physician licensure (strongly preferred)
• Board-certified (strongly preferred), with specialty in pediatrics, genetics, or endocrinology highly desired
• At least 10 years of industry experience (other relevant experience e.g., post-graduate experience in the clinical and/or academic realms may also be considered on a case-by-case basis).  Those with less experience may be considered for a Medical Director position.
• Strong track record of scientific and clinical inquiry
• Possess excellent communication skills (written and oral)
• Demonstrate sound judgement in terms of handling complex, confidential, and regulated information

Key competencies:

You have excellent communication skills, both written and verbal, and you learn quickly, even when working under pressure. You’re able to follow complex instructions, multitask effectively, and still maintain a strong attention to detail. You lead confidently — both through your actions and when guiding others — and you’re known for being a trustworthy, collaborative team player. You take initiative, solve complex problems with ease, and demonstrate sound judgment, especially when handling confidential, sensitive, or regulated information

Travel: Up to 20%.

Office: Ascendis Pharma Headquarters, Tuborg Boulevard 12, 2900 Hellerup, Denmark 

Apply now.

Applications will be evaluated when received, so please apply as soon as possible.

All applications must be submitted in English and are treated confidentially.