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NBE DMPK Lead (all genders), limited for 2 years

icon building Unternehmen : Merck Kgaa
icon briefcase Auftragstyp : Vollzeit

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Arbeitsbeschreibung - NBE DMPK Lead (all genders), limited for 2 years


 


Work Your Magic with us!  


 


Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.  


 


United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.


 


Your Role:


At the intersection of scientific innovation and patient impact, this role places you at the heart of next-generation biotherapeutic development. As the NBE DMPK Lead, you will serve as the authoritative scientific expert for drug metabolism and pharmacokinetics across a portfolio of novel biological entities — including ADCs, AOCs, and multispecific biologics. You will define the DMPK strategy for each molecule, integrating PK, immunogenicity, and bioanalytical approaches to de-risk clinical development and drive health authority submissions. Applying Modeling and Simulation, you will generate data-driven insights to inform molecular design and translate preclinical findings into human dose predictions. Embedded in cross-functional project teams, you will guide peers and senior stakeholders — shaping the scientific direction of your projects.


This position is limited for two years.


 


Who You Are:



  • You hold a degree or equivalent qualification in Pharmacokinetics, Pharmaceutical or Biotechnological Sciences, Biomedical or Chemical Engineering, Applied Mathematics, or a related biological or chemical discipline; a doctoral degree with relevant industry experience is typical for this level.

  • You bring substantial professional experience in the pharmaceutical or biotechnology industry, with deep expertise in PK/PD concepts across drug discovery and development — including translational sciences and regulatory requirements for biotherapeutics such as ADCs, AOCs, and multispecific biologics.

  • You have hands-on experience with quantitative modeling approaches, including M&S tools, population PK software, QSP platforms, or programming environments such as Python or R; experience with AI/ML applications in drug development is a strong advantage.

  • You possess a solid understanding of adjacent disciplines — including pharmacology, toxicology, nonclinical safety, drug design, and bioanalytics — and can integrate insights across these areas to guide biotherapeutic engineering and optimization.

  • You communicate complex scientific concepts clearly and confidently to diverse audiences, including cross-functional project teams and senior stakeholders, and are comfortable influencing decisions without direct authority.

  • You are fluent in written and spoken English; proficiency in German or Italian is an advantage.

  • You bring strong organizational skills, intercultural awareness, and the ability to manage multiple project commitments with a high degree of autonomy.


 


 


What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!


 


Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!


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