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Scientist (m/f/d) Functional Assay

icon building Unternehmen : Glycothera
icon briefcase Auftragstyp : Vollzeit

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Arbeitsbeschreibung - Scientist (m/f/d) Functional Assay



Role Overview


For our site in Jülich (Germany) we are looking for a highly motivated Bench Scientist to join our Functional Assay team. The main area of responsibility will be the development and execution of cell-based assays and/or SPR-based binding assays.



Key Responsibilities and Work assignments


Specifics of the Role:
  • Perform, evaluate and document experiments for method development of functional assays, including cell-based assays (e.g. potency, CDC, ADCC, ADCP, apoptosis assay, proliferation assay) and/or binding assays (e.g. SPR) according to ICH guidelines
  • Handle cell lines and primary cells (e.g. isolation, freezing, thawing, propagation, testing)
  • Analyze samples to support the development of therapeutic candidates across various departments/process steps
  • Perform, evaluate and document functional assays for analytical similarity and comparability studies
  • Draft regulatory documents, including SOPs, R&D-Procedures and development reports
  • Support method validation and method transfer activities
  • Take care of laboratory equipment (e.g., perform instrument maintenance and qualification) and support laboratory management tasks
  • The role will be primarily lab-based




Your profile


Required experience:
  • B.Sc. in relevant scientific discipline (life sciences such as biology, biomedical sciences, biochemistry, biotechnology, etc.) with minimum 3-5 years of relevant work experience, or M.Sc. with 0-1 years of relevant work experience
  • Experience working with mammalian cell lines under aseptic conditions; culture initiation, propagation, cryopreservation; generation of master and working cell banks; separation and purification of primary human cells is a plus
  • Experience with cell-based and bioassay development (e.g., CDC, ADCC, proliferation, apoptosis) for monoclonal antibody analysis
  • Experience with relevant analytical methods (e.g., MSD, ELISA, Flow Cytometry) is advantageous
  • Experience with biochemical and biophysical methods (e.g., binding assays/SPR, concentration determination/CFCA, covalent protein modification, buffer exchange) is advantageous
  • Attention to detail and precise work habits (e.g., documentation, pipetting)
  • Excellent written and verbal communication skills
  • Proficient in using a PC and common Microsoft packages. Experience with specific laboratory instrumentation (e.g., Biacore T200 and 8K, MSD, Flow cytometer, microplate reader) and analysis software (e.g., SoftMax, Methodical Mind, MACSQuantify, Biacore Insight) is a plus.
You are a smart, proactive and solution-driven scientist with a hands-on attitude who is able to independently progress projects, prioritize tasks adequately and work against tight timelines. At the same time you maintain a high-quality standard in your work, support the team and foster a sense of positivity. If this sounds like you, then join us in shaping what’s next!
Language: English, German is highly beneficial.
 Work Experience: Industrial work experience (biotechnology/biopharma) is highly appreciated




Why us?


Our Jülich site with currently 40 employees offers an innovative, vibrant and multicultural environment that gives you the chance to bring in all of your competencies, and together with a highly motivated team drive the change and develop personally. We believe in a culture of respect, trust, reliability and positivity.
Interested? Then please send your full application as a PDF including earliest start date and salary expectations via the application-button.
 
 




Contact information


Glycothera Development GmbH | Karl-Heinz-Beckurts-Str. 13 | 52428 Jülich
 
 Become part of GlycoThera and grow with us!




About us


GlycoThera Pharmaceutical Services is a leading global service provider for contract development and analytics for biotherapeutics at all stages of product life cycle. With our expertise in the development of biologics (recombinant proteins such as monoclonal antibodies, cytokines and hormones), manufacturing sciences, analytics, quality control and regulatory strategy we support a broad range of clients globally, from emerging biotech startups to leading global pharmaceutical companies.





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Über das Unternehmen

Glycothera

GlycoThera Pharmaceutical Services is a leading global service provider for contract development and analytics for biotherapeutics at all stages of product life cycle. With our expertise in the development of biologics (recombinant proteins such as monoclonal antibodies, cytokines and hormones), man...

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