Associate Scientist

JOB DESCRIPTION

Designation: Associate Scientist (8-I) 

Job Location: Bangalore

Department: Biopharmaceutics (BPH)

Reports to: Lead Investigator

About Syngene

Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene’ s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240 – strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.

Job Purpose: Screening for interim/commercial form, small scale crystallization process   development and milling activities towards enabling drug development

Key Responsibilities:

• Polymorph and salt screening of NCEs to enable form endorsements for IND TOX and FIH


• Small scale crystallization process development and jet milling activities.


• Handling instruments for solid state characterization like PXRD, DSC, TGA, DVS, Microscope, Hot stage and UPLC/HPLC.


• Record, summarize and present experimental results. Draft scientific reports


• Prepare presentations for internal and external stakeholders and present them in relevant forums


• Lab and inventory management


• Good working knowledge of MS office and other relevant scientific software tools

Educational Qualifications & Experience:

M.Sc. or M.Pharm. or M.Tech in Chemistry/ / Pharmaceutical chemistry/ Physical Chemistry

Technical Skills:              

• Understanding and sound knowledge of polymorph and salt/co-crystal screening techniques


• Basic knowledge of solid-state characterization tools and preferably having hands-on experience on PXRD, DSC, TGA, DVS, UPLC/HPLC


• Good understanding of thermodynamics and kinetics


• Knowledge in basics of nucleation and crystal growth


• Basic understanding on theory of crystallization process development and size reduction techniques

Functional/Behavioral Skills:

• Ready to learn new technologies and adapt to novel workflows


• Be a team player and work with the analytical team for data acquisition and interpretation


• Cross-functional collaboration internally as well as with external stakeholders while exhibiting the core values of the company


• Good oral and written communication and presentation skills

Interfaces & Dependencies:

Internal: Candidate will be interacting with (solid state characterization, Chemical development for API supply (CDAS) and analytical research and development (ARD) groups

 External: Candidate will have occasional interactions with Syngene’ clients working in Material  Science and Engineering as well as discovery and development pharmaceutics.

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.