Lead Scientist - Medicinal Chemistry

JOB DESCRIPTION

Designation: Lead Scientist – Medicinal Chemistry

Job Location: Syngene International Limited, Bangalore

About Syngene

Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene’ s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.

Job Purpose:

Personnel handling this profile will be responsible for performing reactions, documenting the observations in relevant lab notebooks or e-books and follow instructions from the supervisor and work in a group (or individually) to accomplish the tasks in a timely and efficient manner. They are also responsible for assisting the supervisor to alert shortfall of resources and train junior scientists to develop their technical skills

Key Responsibilities:

• Perform synthetic chemistry reactions, reaction workups, purification of the compounds by column chromatography, crystallization, re-crystallization techniques, preparative TLC and operating lab equipments


• Assist the supervisor to take stock of resources (raw materials, solvents, etc.) in the project and report any shortfall and search literature using Reaxys


• Provide hands-on training and supervision to juniors while performing synthesis of compounds


• Ensure that the samples generated during the course of synthesis are given for analysis and record subsequent results obtained and update the supervisor / group leader on the progress of synthesis and ensure samples are packed appropriately for shipment


• Record the observations of experiment/reaction, results, utilization of resources and other activities related to the reaction in the laboratory or e-notebook following guidelines and in timely manner and ensure that the same is handled safely and confidentially.


• Ensure that the instrument / equipment are calibrated, undergone preventive maintenance and are kept clean before use and in case of any breakdown, report to maintenance immediately


• Ensure that they know the MSDS of the chemicals they are handling and aware of emergency response procedures in case of accidental spillage, leakage or fire and ensure proper waste segregation as per EHS norms


• Always follow EHS and quality system requirements in the workplace ensuring individual safety and lab safety


• Attend all mandatory training and update training records as and when training is completed


• Always ensure confidentiality


• Prepare SOPs/IOPs/EOPs/OCPs when any new lab activity is identified or existing one requires updation


• Any other lab responsibilities as indicated by the EHSQ team member/ supervisor / group leader.

Educational Qualification:

M.Sc in General or Organic chemistry

Technical/functional Skills:

• Good knowledge in Synthetic Organic Chemistry and excellent experimental skills (success rate of reaction >80%)


• Handling of some specialized technical reactions including hazardous/exothermic/sensitive reactions


• Familiar with operations of relevant apparatus - instrument / equipment.


• Good Knowledge of analytical techniques and analytical data interpretation.


• Good communication skills

Experience:

Seeking a mid‑experienced chemist with hands‑on CRO exposure.

Behavioral Skills:

• Able to work independently and make decisions with minimal supervision


• Good interpersonal skills


• Good team player

Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodation for qualified individuals with disabilities.