Scientist III, Protein biology

Work Schedule

Environmental Conditions

Job Description

As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.

DESCRIPTION:
Join our innovative team as a Scientist III in Protein Biology, where you'll contribute to advanced research in antibody development and validation. In this role, you'll manage projects focused on developing and optimizing antibodies using advanced molecular and cell biology techniques. Working in our well-equipped facilities, you'll collaborate with cross-functional teams to advance product development from concept to commercialization.

You'll contribute to pioneering research while supporting junior scientists, establishing technical protocols, and ensuring the highest standards of scientific excellence. This position offers the opportunity to work with advanced technology and innovative methodologies in protein design and engineering. Your expertise will be important in driving product quality and advancing our mission of enabling our customers to make the world healthier, cleaner, and safer.

This is an individual contributor role.

REQUIREMENTS:
• PhD with greater than 5 years’ experience in a life sciences field with a strong focus on structural biology, protein design and engineering. Minimum 3-4 years of industrial experience is preferred.
• Preferred Fields of Study: Biotechnology, Life Sciences, Molecular Biology, Immunology, Cell Biology

Nature of experience:

• Extensive experience in the antibody development and engineering field including hybridoma, single B cell, and other recombinant antibody platforms
• Expert in the field of peptide and protein design, expression, purification, and protein-protein interaction (Structure -function -relationship)
• Thorough understanding of antigen/immunogen properties, design and development towards eliciting desired antibody response
• Extensive experience in structural biology, antibody and protein engineering, computational modeling and rational design.
• Experience with expression and purification of recombinant proteins from bacterial, yeast, insect and mammalian systems is preferred
• Expertise in development of conjugation chemistries or performing antibody conjugations is desired
• Broad knowledge and experience in molecular biology, cell biology, immunoassays, protein design, engineering, purification, and conjugation fields to enable successful delivery on program goals
• Thorough in biochemical and immunoassay workflows such as ELISA, SDS-PAGE, Western blotting, IF, IHC
• Ability to provide technical trouble shooting to resolve scientific problems.
• Experience in authoring and optimizing standard operating procedures with a focus on reproducibility
• Skills for identifying deviations from expected outcomes, problem solving and suggesting alternatives
• Excellent written and verbal presentation skills
• Experience in leading product launches through knowledge and application of product commercialization processes including feasibility, development, and validation stages
• Proven leadership skills and ability to work alongside colleagues from different backgrounds
• Experience with leading and mentoring people either with or without direct reporting structure
• Strong, independent understanding of standard and emerging research protocols and techniques are preferred. GLP experience is a must.