Senior Scientist I / Senior Scientist II, Documentary Standards (Chemical Information)

At USP, we value inclusive scientific collaboration and recognize that attracting diverse expertise strengthens our ability to develop trusted public health standards. We foster an organizational culture that supports equitable access to mentorship, professional development, and leadership opportunities. Our partnerships, standards, and research reflect our belief that ensuring broad participation in scientific leadership results in stronger, more impactful outcomes for global health.

USP is proud to be an equal employment opportunity employer (EEOE) and is committed to ensuring fair, merit-based selection processes that enable the best scientific minds—regardless of background—to contribute to advancing public health solutions worldwide. We provide reasonable accommodations to individuals with disabilities and uphold policies that create an inclusive and collaborative work environment.

Brief Job Overview

This is an independent contributor scientific position in the Small Molecules Department (SM) reports to the Sr. Manager. The successful candidate will be responsible for creating, managing chemical structure files based on sponsor submission data to support the development of monographs for drug substances and associated dosage forms in the USP-NF. This role requires active communication with Small Molecules and other PUTs, Reference Standards Scientists, GSRS team, Reference Standards Laboratories (RSL), and Analytical Development Laboratories (ADL) and other departments such as Publications (PUBS), SCD, Procurement department.

How will YOU create impact here at USP?

 As part of our mission to advance scientific rigor and public health standards, you will play a vital role in increasing global access to high-quality medicines through public standards and related programs. USP prioritizes scientific integrity, regulatory excellence, and evidence-based decision-making to ensure health systems worldwide can rely on strong, tested, and globally relevant quality standards.

Additionally, USP’s People and Culture division, in partnership with the Equity Office, invests in leadership and workforce development to equip all employees with the skills to create high-performing, inclusive teams. This includes training in equitable management practices and tools to promote engaged, collaborative, and results-driven work environments.

The Sr. Scientist I/II has the following responsibilities:

• Create and update chemical information files based on data submitted by external collaborators and sponsors.


• Review and validate chemical data for accuracy, consistency, and compliance with internal standards.


• Edit and manage chemical information using the GSRS platform and Excel-based tools.


• Collaborate with a team of scientists to support the development and continuous improvement of chemical information files.


• Utilize cheminformatics software (e.g., ChemDraw, ISIS) for developing chemical structures and other chemical information.


• Conduct comprehensive searches using chemical databases and tools such as SciFinder, ChemSpider, USAN, INN, and PubMed.


• Support literature and patent research using platforms like Reaxys and PubChem.


• Work closely with IT and data science teams to integrate chemical information systems with enterprise data platforms.


• Engage with USP staff, regulatory bodies, stakeholders, and other pharmacopeias to support monograph development.


• Collaborate with internal departments including Reference Standards Development (RSD), Analytical Development Laboratories (ADL), Publications, and Compendial Operations on monograph-related initiatives.


• Experience working with biologic molecules and excipients is a strong plus.


• Strong communication and collaboration skills across scientific and technical teams.


• Familiarity with regulatory and pharmacopeial standards and processes.


• Participate in cross-functional teams and contribute to strategic initiatives.


• Perform additional duties as assigned to support departmental goals.

Who is USP Looking For?

The successful candidate will have a demonstrated understanding of our mission, commitment to excellence through inclusive and equitable behaviors and practices, ability to quickly build credibility with stakeholders, along with the following competencies and experience:

Experience Required

 Senior Scientist I: MSc - Organic Chemistry with minimum 11 to 13 years relevant experience; or Ph.D. degree in Organic Chemistry, or a related scientific field with 7 to 10 years.

Senior Scientist II: MSc - Organic Chemistry with minimum 13 to 15 years relevant experience; or Ph.D. degree in Organic Chemistry, or a related scientific field with 10 to 13 years

Additional Desired Preferences

Desired preferences are to showcase any additional preferred levels of expertise to perform the role. Reminder: any items listed in this section are not requirements nor disqualifies for candidate consideration.

• Expert in naming organic compounds using the IUPAC naming convention


• Broad knowledge of organic chemistry and chemical reactions


• Experience using the United States Pharmacopeia or other global pharmacopieas is a plus. 


• Experience with the Global Substance Registration System is a plus


• Previous experience working in the Pharmaceutical Industry is a plus


• Expertise in the degradation chemistry of organic compounds is a plus. 

Supervisory Responsibilities

None, this is an individual contributor role.

If yes, what is the number of direct reports and their titles?

Benefits

USP provides the benefits to protect yourself and your family today and tomorrow. From company-paid time off and comprehensive healthcare options to retirement savings, you can have peace of mind that your personal and financial well-being is protected.

 Note: USP does not accept unsolicited resumes from 3rd party recruitment agencies and is not responsible for fees from recruiters or other agencies except under specific written agreement with USP.