Site Activation Lead

ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development

At ICON, study start-up is not a checklist — it’s the moment where strategy becomes access. As a Site Activation Lead, you ensure clinical trials move from plan to reality without unnecessary delays, protecting timelines, budgets, and most importantly — patient access to new therapies.

This role is about ownership, impact, and performance.

What You’ll Be Responsible For — and Why It Matters

• Design and lead Study Start-Up Plans- So that every country and site moves forward with clarity, alignment, and realistic timelines.

• Drive regulatory and ethics submissions to approval - So studies reach activation faster and without avoidable rework or compliance risk.

• Oversee site contracts and budget negotiations - So financial and legal barriers don’t delay first patient in.

• Identify risks early and implement mitigation strategies - So roadblocks are prevented — not reacted to.

• Partner with sponsors at Bid Defences and Kick-Off Meetings - So start-up strategy is strong from day one and aligned with expectations.

• Lead and empower regional start-up teams - So performance is consistent, accountable, and milestone-driven across countries.

• Ensure data accuracy, reporting, and KPI tracking - So sponsors have transparency and projects stay on course.

Every action you take directly influences time-to-activation — and ultimately, time-to-treatment for patients.

What You Bring

• 5+ years in Clinical Research with strong Study Start-Up experience

• Deep understanding of regulatory frameworks and submission processes

• Proven ability to lead cross-functional teams globally

• Strong project management and risk mitigation skills

• Confidence in sponsor-facing environments

#LI-MK1

What ICON can offer you:

Visit our careers site to read more about the benefits ICON offers.

At ICON, inclusion & belonging are fundamental to our culture and values.   We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

Are you a current ICON Employee? Please click here to apply