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2025_116 Bioinformatician Cancer Drug Resistance Project

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Descripción del trabajo - 2025_116 Bioinformatician Cancer Drug Resistance Project



JOB DESCRIPTION


The Oncology Translational Research (OTR) group is seeking a highly motivated bioinformatician with strong analytical skills and solid background in cancer biology to join a translational oncology project focused on uncovering mechanisms of drug resistance in ovarian cancer using advanced omics and spatial transcriptomics data. The position is based at the Germans Trias i Pujol Research Institute (IGTP), within a multidisciplinary team working with 3D models (organoids) and patient-derived samples.




MAIN RESPONSIBILITIES


  • Analyze spatial transcriptomics and multi-omics datasets from cancer-patient samples.
  • Develop and optimize bioinformatics pipelines.
  • Integrate and interpret data to identify molecular mechanisms of drug resistance.
  • Collaborate in manuscript preparation and presentation of results.
  • Participate in project meetings and contribute to strategic planning.




QUALIFICATIONS AND EXPERIENCIE


Education:
  • PhD in Bioinformatics (or currently in the final year of PhD), a MSc in Genetics, Bioinformatics, or related fields, and an Undergraduate degree in Biology or similar, with a strong academic record.
Languages:
  • Fluent in English (written and spoken).
Specific knowledge:
  • Experience analyzing multi-omics data (RNA-seq, ATAC-seq, proteomics).
  • Familiarity with spatial transcriptomics platforms (e.g., Visium, Xenium).
  • Skilled in R and Python programming.
  • Proficient in Linux environments and HPC/cloud computing.
  • Knowledge of cancer genomics and proteogenomics.
Personal skills:
  • Excellent communication and interpersonal skills.
  • Ability to work independently and collaboratively.
  • Strong organizational and problem-solving abilities.
Experience:
  • Demonstrated experience in cancer-related bioinformatics research.
  • Prior involvement in international collaborations and multidisciplinary projects.
Specific conditions of the call:
  • The position is funded through a competitive grant; candidates with fellowships or experience in funded projects will be positively evaluated.
Additional valued knowledge:
  • Experience with explainable AI approaches in omics data analysis.
  • Familiarity with driver mutation analysis and post-translational modification studies.
  • Publication record in high-impact journals.
  • Working knowledge of Spanish and/or Catalan is a plus.




WHAT WE OFFER


  • Temporary contract until the end of the project (31-12-2025).
  • Full time contract.
  • Gross annual remuneration inherent to the square objected to this call, will be fixed based on the experience provided and the skills of the candidate, distributed in 12 payments.
  • Flexible payment (childminding vouchers).
  • 23 days holiday and 5 days for personal matters.
  • Training capsules by the company.
  • Be part of an excellent multidisciplinary research centre with the HRS4R badge.
  • Location on the Can Ruti Campus, a first-class translational research environment in the Barcelona area, in a very stimulating scientific environment. The IGTP offers a supportive, friendly and collaborative ecosystem to promote professional development and help you achieve your research goals.





HOW TO APPLY


Interested persons must attach to the application:
  • Motivation letter explaining their interest in the position.
  • Updated CV.
  • Contact of 2-3 references.
Applications will be evaluated in accordance with the guiding principles and objectives of the supply systems, following the process described below:
  1. Curricular evaluation: analysis of the curriculum vitae to assess aspects related to training, professional career and experience in positions related to the job position under selection.
  2. Personal interview: once the résumé has been evaluated, the selected candidates will be called for a personal interview to verify and expand on the information detailed in the résumé and to evaluate aspects related to experience and professional skills.
Applications that do not meet the requirements, that are not included in the cases foreseen or that are not processed in accordance with the established procedure will not be considered in the selection process.




DEADLINE FOR APPLICATIONS


The call for applications will close on October 12th.




About us


The Germans Trias i Pujol Research Institute (IGTP) is a public research centre located in Badalona. Its main objective is to increase scientific knowledge in order to transform it into solutions to improve the health and medical care of patients and the community.

The Institute is associated with one of the major university hospitals in the Barcelona area, the Germans Trias i Pujol Hospital, and is part of the Can Ruti biomedical campus. IGTP is a CERCA centre and is also accredited as a centre of excellence by the Instituto de Salud Carlos III (ISCIII) and is in charge of coordinating the management and scientific strategy of the campus, working in close collaboration with the other centres.

The Germans Trias i Pujol Research Institute carries out research within 9 areas

  • Cancer
  • Cardiovascular and Respiratory Diseases
  • Community Health
  • Diseases of the Liver and Digestive Tract
  • Endocrine and Diseases of the Metabolism, Bones and Kidneys
  • Immunology and Inflammation
  • Infectious Diseases
  • Neuroscience
  • Science of Behaviour and Substance Abuse
Scientists working in these areas publish an average of over 900 papers a year, contribute to improved treatment and healthcare protocols, produce patents and set up spin-off companies in order to improve the lives of patients.  

The following video is a bird's eye view of Campus Can Ruti a top-tier translational research environment in the Barcelona area, in a very stimulating scientific environment. The IGTP offers a supportive, friendly and collaborative ecosystem to promote professional development and help you achieve your research goals.    

The IGTP, in its commitment to equal opportunities, guarantees equal treatment between candidates and persons with a degree of disability equal to or greater than 33 per 100, as accredited by the Spanish Autonomous Regions or the State Administration, or who have been declared to have a total permanent disability in a different profession through a resolution of the National Institute of Social Security, while retaining functional capacity for the completion of the tasks of the post will be positively considered.




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