The Badalona Neuromuscular Research Group (GRENBA) is a multidisciplinary team made up of specialised basic and traslational researchers in the laboratory at IGTP and clinical staff from the Neurology and Paediatric services at Germans Trias i Pujol University Hospital.
Our main goal is to find solutions for patients with neuromuscular diseases and, to achieve this, our team draws on its extensive clinical experience in the diagnosis and treatment of these patients, and has recently built up a strong patient base.
In the laboratory, we have extensive experience in genetic, epigenetic, transcriptomic and proteomic techniques to study the pathogenicity of the most prevalent neuromuscular diseases such as myotonic dystrophy type I, Duchenne muscular dystrophy and glycogenosis V at the molecular level. Our team also has experience in generating patient-derived cellular models and in designing and testing new treatments in vitro, in vivo and in patients. In addition, we work on numerous collaborative projects with national and international researchers also involved in the study of these neuromuscular pathologies.
The line of research in which the candidate would work focuses on Duchenne muscular dystrophy (DMD), the most prevalent muscular dystrophy in childhood, which is a very severe genetic muscle disorder marked by progressive muscle degeneration, in which chronic inflammation, fibrosis and fat deposition replace functional muscle tissue over time. Building on previous studies in our group, we are exploring a new emerging therapeutic target to 1) reduce fibrosis, intramuscular fat accumulation and inflammation in DMD, and 2) decipher the molecular mechanisms involved.
- Co-direction of projects applied in competitive calls in the context of neuromusculars diseases, focusing on fibroadipogenesis and muscle regeneration
- Co-supervision of undergraduate, master’s and doctoral students.
- Actively seeking funding through public and private calls
- Writing scientific papers and disseminating project results
- Cell culture of humans and mouse cells and cell transfections experiments
- Cell toxicity and cell viability tests
- WB and qPCR analyses
- Immunocytochemistry and immunohistochemistry techniques
- Microscopy and image analyses
- FAC sorting
- Metabolic studies
- Animal experimentation with mouse models
Candidate must comply with the MSCA Postdoctoral Fellowships 2025 (HORIZON-MSCA-2025-PF-01) eligibility criteria set by the call:
- Supported fellows: Must be in possession of doctoral degree. At the call deadline (10-09-2025), supported researchers must have a maximum of 8 years full time equivalent experience in research, measured from the date that the researcher was in a possession of a doctoral degree and certified by appropriate documents.
- Nationality: Any.
- Mobility: The researcher must not have resided or carried out his/her main activity (work, studies, etc.) in the country of the host organization for more than 12 months in the 3 years immediately prior to the deadline.
- Researchers wishing to reintegrate from a third country must either be based in a third country at the call deadline, or have moved directly from a third country to an EU Member State or Horizon Europe Associated Country within the last 12 months before the call deadline.
- Must be fluent in English (both written and spoken)
- Priority will be given to candidates with an outstanding record of research achievements and publications.
- Experience in cellular and molecular biology techniques is required
- Proven experience with animal modelling handling (mouse or zebrafish) will be a plus.
- Experience in application and writing of articles and research projects will be a plus.
- We are looking for talented, innovative and hard-working young scientists who are highly motivated to do research in the field of neuromuscular diseases.
Contribution for the recruited researcher per person monthly:
- Living allowance: 5990€
- Mobility allowance: 710€
- Family allowance (if applicable): 660€ x % covered by the beneficiary
- Long-term leave allowance (if applicable): 6700€
- The selected candidate will be incorporated upon obtaining an MSCA-PF-2024 or similar fellowship.
- Flexible payment (childminding vouchers).
- 23 days holiday and 5 days for personal matters +2 days for Easter + 2 days for Christmas .
- Training capsules by the company.
- Be part of an excellent multidisciplinary research centre with the HRS4R badge.
- Location on the Can Ruti Campus, a first-class translational research environment in the Barcelona area, in a very stimulating scientific environment. The IGTP offers a supportive, friendly and collaborative ecosystem to promote professional development and help you achieve your research goals.
https://marie-sklodowska-curie-actions.ec.europa.eu/calls/msca-postdoctoral-fellowships-2025Interested persons must attach to the application:
- Motivation letter explaining their interest in the position.
- Short CV (max 2 pages)
- Contact of 2-3 references.
Applications will be evaluated in accordance with the guiding principles and objectives of the supply systems, following the process described below:
- Curricular evaluation: analysis of the curriculum vitae to assess aspects related to training, professional career and experience in positions related to the job position under selection.
- Personal interview: once the résumé has been evaluated, the selected candidates will be called for a personal interview to verify and expand on the information detailed in the résumé and to evaluate aspects related to experience and professional skills.
Applications that do not meet the requirements, that are not included in the cases foreseen or that are not processed in accordance with the established procedure will not be considered in the selection process.
- Deadline of the next call for proposals for MSCA - Postdoctoral Fellowships is September, 10th 2025.
- You can send this Expression of interest to the contact person before 15/06/2022
- Proposals will be pre-selected on the basis of internal evaluation. Candidates will be informed of the results.
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