The Childhood Liver Oncology Group (c-LOG) is recruiting a junior researcher in preparation for applying for predoctoral PhD grants.
c-LOG is a young, dynamic and motivated team committed to advancing our understanding of childhood liver cancer. Our focus is on hepatoblastoma, a rare paediatric tumour whose incidence is increasing globally, highlighting the need for further research to improve diagnosis, treatment and outcomes.
Due to its low mutational burden, hepatoblastoma presents unique challenges, requiring researchers to investigate alternative pathways to understand its development. Studying the proteome and tumour microenvironment could lead to the discovery of diagnostic/prognostic biomarkers and therapeutic targets, offering the potential for innovative treatment strategies.
Key areas of interest include:
- Validating diagnostic and prognostic biomarkers of hepatoblastoma and other childhood liver tumours by analysing proteomic databases.
- Glycosylation patterns in hepatoblastoma, which may play a crucial role in tumour biology and progression.
- Integrating the findings with molecular databases generated by the team.
The candidate will conduct this research within the framework of prestigious projects funded by Horizon Europe (THRIVE) and the Scientific Foundation of the Spanish Association Against Cancer (
www.PMed4HB.eu). A major strength of our group is access to a comprehensive and unique biorepository of patient samples collected from across Europe, from the PHITT international clinical trial (Paediatric Hepatic International Tumour Trial, NCT03017326), offering a unique translational research perspective.
The importance of this research is amplified by the limited treatment options currently available for children with advanced or aggressive forms of the disease. Working in this field represents a unique opportunity to contribute to breakthroughs in pediatric oncology.
This PhD opportunity also allows candidates to collaborate with an experienced team on hepatoblastoma research, recognized for significant contributions to the field.
The candidate will be involved in the ongoing research projects of our group such as:
- Biomarker discovery and validation in retrospective and prospective cohorts from childhood liver cancer patients.
- Study of the proteomic expression profiling in childhood and adult liver cancer.
- Clean, validate, and manage large datasets using Power BI and potentially other relevant data analysis tools.
- Bachelor's degree in life sciences with high qualification marks, suitable to apply for pre-doctoral grants (minimum 8.5/10 in the Bachelor’s degree)
- Master’s degree.
- Desirable experience:
- Previous experience on laboratory techniques
- Abroad laboratory experience of minimum 3 months
- R knowledge and bioinformatic analysis of “omic” data
- Ability to work as a team
- Good verbal and written English level.
- High motivation to perform research in the pediatric oncology field
- A full-time employment contract
- Inmediate incorporation
- Gross annual remuneration inherent to the square objected to this call, will be fixed based on the experience provided and the skills of the candidate, distributed in 12 payments.
- Flexible payment (childminding vouchers).
- 23 days holiday and 5 days for personal matters.
- Training capsules by the company.
- Be part of an excellent multidisciplinary research centre with the HRS4R badge.
- Location on the Can Ruti Campus, a first-class translational research environment in the Barcelona area, in a very stimulating scientific environment. The IGTP offers a supportive, friendly and collaborative ecosystem to promote professional development and help you achieve your research goals.
Interested persons must attach to the application:
- Motivation letter explaining their interest in the position.
- Updated CV.
- Contact of 2-3 references.
Applications will be evaluated in accordance with the guiding principles and objectives of the supply systems, following the process described below:
- Curricular evaluation: analysis of the curriculum vitae to assess aspects related to training, professional career and experience in positions related to the job position under selection.
- Personal interview: once the résumé has been evaluated, the selected candidates will be called for a personal interview to verify and expand on the information detailed in the résumé and to evaluate aspects related to experience and professional skills.
Applications that do not meet the requirements, that are not included in the cases foreseen or that are not processed in accordance with the established procedure will not be considered in the selection process.
The call for applications will close on 6th June 2025.
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