DMPK Project Leader - Immediate Start

We are looking to hire a confident DMPK Project Leader to join our awesome team at Astrazeneca AB in Göteborg.
Growing your career as a Full Time DMPK Project Leader is an awesome opportunity to develop relevant skills.
If you are strong in communication, decision-making and have the right personality for the job, then apply for the position of DMPK Project Leader at Astrazeneca AB today!

Are you an experienced drug discovery scientist with expertise in pharmacokinetics, pharmacology and drug metabolism (DMPK)? Would you like to apply your expertise in a global company that follows the science and turn ideas into life changing medicines? Then you could be the new colleague we are looking for! We are now looking for an experienced and motivated individual to join the team as a DMPK Project Leader. The position is placed at AstraZeneca's dynamic R&D site in Gothenburg, Sweden. Working at AstraZeneca means being entrepreneurial, following the science, scrutinizing data and details simultaneously with holistic thinking and through teamwork make progress. Respiratory & Immunology is one of the three main therapeutic research areas within AstraZeneca. Early R&I is a global function, with research units in Gaithersburg (US), Cambridge (UK) and Gothenburg (Sweden), and delivers candidate drugs into late-stage clinical development. DMPK interacts with other functions in supporting Early R&I projects all along the value chain, from target selection all the way to market launch and Life cycle management. What you'll do With a true passion for drug discovery you will support our portfolio within the R&I therapeutic area. In the DMPK project lead role you will work collaboratively with project representatives from other disciplines. These may include biology, antibody Discovery/Protein Engineering, medicinal chemistry, safety , clinical pharmacology, and pharmaceutical sciences, where your task is to influence candidate profiling by providing the necessary DMPK support for clinical investigations. It is your responsibility to ensure delivery of all DMPK related activities. These include preclinical PK experiments, in vitro ADME and biotransformation to yield pharmacokinetic understanding. Furthermore, assisting design of pharmacodynamic studies that ultimately delivers a pharmacological assessment underpinning human dose prediction. You will work on projects from candidate selection to Phase 2a. We believe that you have a solid understanding of DMPK, a working knowledge of pharmacology, and that you will be able to provide expert advice and interpretation of complex drug discovery data. Main duties and responsibilities;

• Communicate scientific progresses both externally and internally
• Deliver DMPK input and data to projects within agreed timelines and to the right quality
• Apply an understanding of DMPK to support/influence compound profiling, project progression and project strategy
• Define and deliver a translational quantitative PKPD strategy in projects, so that effective conclusions can be made
• Contribute to estimation of safety margins and report results and interpretations to project teams and internal governance bodies
• Responsible for leading, coordinating and engaging with R&I DMPK colleagues in project related activities
• Prepare clear presentations related to the above for internal governance bodies

Essential for the role

• PhD or equivalent experience in a relevant field
• Expert in DMPK sciences with profound knowledge of drug discovery and development processes
• Broad experience in biologics drug development (PK & Bioanalysis)
• Experience with regulatory submissions for biologics and small molecules
• Good knowledge of all DMPK assays including the use of in silico tools for PK prediction
• Experience in project leadership
• Collaborative mindset
• Team player
• Proactive and good communication skills

Why AstraZeneca? At AstraZeneca we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development. What's next! If you are ready to make a difference - apply today, and we'll make it happen together! We welcome your application until March 26, 2023.

Benefits of working as a DMPK Project Leader in Göteborg:

● Excellent benefits
● Opportunities to grow
● Competitive salary