ROLES AND Responsibilities

This position will be dedicated to the Cell Culture Automation department, under the supervision of Senior Scientist

• Ensure cell culture laboratory activities dedicated to the maintenance of CHO cell lines (passaging, batch/fed batch evaluation, cell banking and expansion, cell line productivity and stability evaluation)
• Support the implementation of an automated cell cultivation platform involving cutting-edge technologies and best-in-class equipments
• Understand and execute automation procedures using complex integrated liquid handling platform and custom devices
• Participate to experimental designs to evaluate and characterize automated process performances using Design of Experiments (DoE)
• Perform control tests to monitor cell culture parameters through manual and automated processes
• Identify critical cell culture parameters, address bottlenecks in processes/workflows, participate to troubleshooting activities
• Participate to the characterization of optimized cell culture processes and execute optimization programs to support process improvement activities
• Independently plan and execute experiments according to preestablished plans, timelines and priorities
• Participate to the establishment of protocols and documentation required for process validation and platform certification
• Provide continuous efforts in developing and implementing innovative technologies, methods and improvements
• Support in equipment maintenance, interaction with equipment vendors
• Cooperate with internal team collaborators (CLD, R&D, Operations, Analytics) to troubleshoot biology, process or mechanical errors
• In a later phase, support global Cell Line Development activities
• Generate data templates and records. Organize and maintain meticulous records on all conducted experiments
• Manage data analysis, data visualization, verify data integrity and provide technical reports
• Present data at team meetings

This position will require engagement to weekend call-outs and operate at distance or on site if necessary.

Qualifications

• Strong experience in mammalian cell cultivation
• Advanced experience using DoE software (e.g. MODDE) and Excel VBA is a plus 
• Experience with lab automated systems is preferred (e.g. Hamilton liquid handler) and automation scheduling software is a plus
• Experience with Raman spectroscopy is a plus
• Capacity to generate, manage, analyze, and maintain critical data
• Understand project timelines and priorities is essential
• Strong attention to details, time management and organizational skills
• Ability to work independently and as part as a collaborative team