Principal Scientist / Associate Scientific Director - Computational Chemistry

ROLE OVERVIEW

A leading company in the industry is seeking a Principal Scientist / Associate Scientific Director – Computational Chemistry to join their team based in the Chapel-en-le-Frith area, with a hybrid working model. Remote working from home can also be considered.

As the Principal Scientist / Associate Scientific Director, you will be instrumental in solving complex drug discovery challenges and guiding medicinal chemistry programmes.

KEY DUTIES AND RESPONSIBILITIES:

Your duties as the Principal Scientist / Associate Scientific Director will be varied however the key duties and responsibilities are as follows:

1. Deliver high-quality computational chemistry support across drug discovery programmes, from target identification through to clinical candidate nomination.

2. Apply structure-based and ligand-based small molecule drug design methods, including docking, QSAR, pharmacophore modelling, virtual screening, MD, and QM calculations, to guide medicinal chemistry and solve complex design challenges.

3. Provide expert guidance to medicinal chemists and multidisciplinary project teams, integrating computational insight with experimental data.

4. Mentor and develop computational chemists, setting high standards for scientific thinking, quality, and integrity.

ROLE REQUIREMENTS:

To be successful in your application to this exciting role as the Principal Scientist / Associate Scientific Director we are looking to identify the following on your profile and past history:

1. Relevant degree in computational chemistry or a closely related discipline.

2. Proven industry experience in drug discovery within pharma, biotech, or CRO settings, managing client projects.

3. A working knowledge and practical experience with structure-based and ligand-based small molecule drug design and the practical application of computational tools.

Key Words: Principal Scientist / Associate Scientific Director / Computational Chemistry / Drug Discovery / Medicinal Chemistry / Structure-Based Design / Ligand-Based Design / QSAR / Pharmacophore Modelling / Virtual Screening

Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer. We welcome applications from anyone who meets the role requirements. HRS exclusively supports the Life Science sectors, combining recruitment expertise with scientific knowledge to help you advance your career
Only candidates based in UK and eligible to work in UK are allowed