Production Chemist (Rotational shift work required)

Astrea Bioseparations Ltd is a global bioseparations company specializing in the research, development and manufacture of advanced bioseparation products including chromatography adsorbents and columns. Astrea Bioseparations has R&D laboratories in Cambridge, UK and manufacturing facilities on the Isle of Man, British Isles and Canton, Massachusetts, making the company one of the largest volume affinity adsorbent manufacturers in the world.

Astrea Bioseparations is honored to support the biopharmaceutical industry with products and services that help bring lifesaving and improving medicines to market. Regardless of process scale, we are ready to build Purity by Design into each process to ensure quality and speed to market.

The company is now entering an exciting period of growth as we work towards enabling our customers to bring advanced therapies to market using state-of-the-art-purification nanofiber-based technology.

Key responsibilities will include:

Manufacture of established and development products:

• Responsible for batch manufacture of intermediate and final ligands and Chromatographic resins or other products as required.
• Adherence to Standard Operating Procedures (SOP's) and Production Methods.
• Upkeep of accurate production records and notebooks
• Conduct of certain on-line quality control assay
• Analysis of manufacturing data, early identification of anomalies and problems.
• Maintenance of manufacturing equipment and work areas in clean and serviceable state.
• To carry out other work in this area as and when directed by the Production Manager.

Process Development and optimisation

• Responsible for conducting process optimization studies on new and existing processes (both intermediates and final products) to ensure optimum utilization of resources and maximization of yields.
• Responsible for participating in the decision-making processes within the process development and control

Other accountabilities:

• Writing and review/update of SOPs and production methods.
• To share knowledge and train other members of staff as necessary
• Effective time management and work planning to ensure optimum use of all resources

Qualifications, Skills and Experience

• Experience in an industrial chemistry environment.
• Previous experience of a highly regulated manufacturing environment such as pharmaceutical manufacture.
• Previous experience of process development chemistry.
• Computer literate
• Willing to work rotating 12 hour shifts, between days and nights.

We offer a competitive salary and benefits package.