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Principal Mechanical Engineer III (Life Sciences)

salary Salary :

$85 - 92 hourly

Job Description - Principal Mechanical Engineer III (Life Sciences)

Our client, a world leader in biotechnology and life sciences, is looking for a "Principal Mechanical Engineer III” based out in Santa Clara, CA.

Job Duration: Long Term Contract (Possibility Of Extension)

Pay Rate : $85 -$92/hr on W2

Company Benefits: Medical, Dental, Vision, Paid Sick leave, 401K


Job Summary:

You will lead the design and development of next -generation DNA sequencing instrumentation. This is a hands -on, senior -level role focused on solving complex mechanical challenges at the core of highly integrated life science systems.

Responsibilities:
  • Lead end -to -end mechanical design of complex sub -systems, including electro -mechanical, fluidic, pneumatic, and thermal components
  • Design mechanisms for automated reagent and flow cell handling, sealing, and clamping
  • Architect precision thermal control systems (heating, cooling, sensors, condensation control)
  • Collaborate cross -functionally with electrical, systems, consumables, materials, and assay teams
  • Support system integration, verification, and troubleshooting as the technical owner
  • Drive design reviews, manage technical trade -offs, and deliver design documentation (CAD, drawings, specs)
  • Contribute to future system architecture and technology strategy

Skills / Qualifications:
  • PhD + 5 years, MS + 10 years, or BS + 10+ years in Mechanical Engineering, Bioengineering, or related field
  • Hands -on experience designing complex life science, diagnostic, or automation instrumentation
  • Strong expertise in fluidics systems (pumps, valves, tubing, sensors)
  • Proven experience in thermal management and precision temperature control
  • Advanced proficiency in 3D CAD (SolidWorks preferred)
  • Experience with prototyping, testing, and manufacturing processes (machining, injection molding, 3D printing)
  • Familiarity with Python, LabVIEW, or similar tools for device control and data acquisition
Preferred Qualifications

  • Experience with NGS or genomics instrumentation
  • Use of CFD / FEA to guide design decisions
  • Experience in regulated product development environments
  • Demonstrated technical leadership and mentoring experience
If interested, please send us your updated resume at [email protected].

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