Sr. Research Associate, Single Cell Assay Productization (Contract) (P-4977)

We are seeking a Senior Research Associate to join the Assay Productization team to support the development and commercial launch of new Single Cell Genomic products on a six months contract basis, with the potential to extend. Assay Productization acts as the interface between R&D and Production. The team is involved in all stages of product development from concept to post-launch activities. This is a unique cross-disciplinary position that will work closely with a variety of groups including Molecular Biology, Chemistry, Microfluidics, QC, and Manufacturing, to develop and validate novel reagents for the rapid expansion of 10x product lines. Candidates must have a broad working knowledge of molecular biology and be able to apply that knowledge creatively and independently in a fast-paced work environment. Research experience with DNA oligos, antibody assays, RNA assays, and next generation sequencing (NGS) is desired.  Experience in new product introduction and manufacturing operations is a big plus.This role requires a candidate who can be relied upon to produce consistent, high-quality data without needing daily tasks assigned. 

What You Will Be Doing:

• Create NGS libraries from single cells, tissues, or isolated DNA/RNA using 10x instruments and consumables. 


• Preparation, formulation, and testing of newly designed 10x reagents either from SOPs or R&D protocols.


• Assist with reagent guard banding and stability studies.


• Assist with new QC method development and implementation to assess reagent quality through a variety of analytical and functional tests.


• Perform troubleshooting analysis of failed experiments and reagent issues as they arise in the product line.


• Facilitate successful handoffs from R&D to Operations by training QC and Production staff on new workflows or methods.


• Present your own work to internal stakeholders, providing clear explanations of methodology and data interpretation.

Minimum Qualifications:

• BS or MS in molecular biology, biochemistry, genetics, analytical chemistry, or related fields.


• 3+ years (BS) or 2+ years (MS) of experience in reagent or assay development, preferably within the Biotech industry.


• Deep understanding of molecular biology and hands-on experience with NGS library generation and data evaluation.


• Mastery of analytical techniques including qPCR, nucleic acid isolation, and use of Bioanalyzers or real-time PCR instruments.


• Ability to perform complex multi-step experiments with detailed and diligent attention to planning, organization, hands-on technique, and record keeping.


• Experience troubleshooting molecular biology-based assays.


• Strong collaboration and communication skills.


• Desire to work in a flexible and fast-paced startup environment.

Preferred Qualifications:

• Previous work with a variety of NGS sample preparation workflows and analysis. Strong preference for single cell and/or RNA-Seq workflows.


• Past work in a process or product development role, especially technology transfer to manufacturing and/or QC groups.


• Experience working with new and untested reagents.


• Experience creating and optimizing novel assays.

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference. 

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.

10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.