- CDC (Centers for Disease Control and Prevention): Protects public health and safety by controlling and preventing disease, injury, and disability.
- NIH (National Institutes of Health): Conducts and supports medical and behavioral research through 27 separate institutes and centers.
- FDA (Food and Drug Administration): Ensures the safety and efficacy of drugs, medical devices, the food supply, cosmetics, and tobacco products.
- CMS (Centers for Medicare & Medicaid Services): Administers Medicare, Medicaid, the Children's Health Insurance Program (CHIP), and health insurance marketplaces.
- ACF (Administration for Children and Families): Promotes the economic and social well-being of families, children, individuals, and communities.
- ACL (Administration for Community Living): Focuses on maximizing the independence, well-being, and health of older adults and people with disabilities.
- HRSA (Health Resources and Services Administration): Improves access to health care services for people who are uninsured, isolated, or medically vulnerable.
- SAMHSA (Substance Abuse and Mental Health Services Administration): Leads public efforts to advance behavioral health and reduce the impact of substance abuse and mental illness.
- IHS (Indian Health Service): Provides federal health services to American Indians and Alaska Natives.
- AHRQ (Agency for Healthcare Research and Quality): Conducts research to make health care safer, higher quality, more accessible, and more affordable.
- ASPR (Administration for Strategic Preparedness and Response): Coordinates federal medical and public health preparedness and response for disasters and emergencies.
- ARPA-H (Advanced Research Projects Agency for Health): Funds high-risk, high-reward biomedical and health breakthroughs.
- ATSDR (Agency for Toxic Substances and Disease Registry): Protects communities from harmful exposures to hazardous and toxic substances
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