Job Description - Associate Scientist II, Protein Sciences
Work closely with the protein sciences team to engineer and validate binding of antibodies and antibody conjugates at various production scales. Design, plan, and perform protein binding experiments to support in vitro and in vivo evaluations, contributing to project-related scientific activities with some guidance from team members. Utilize UV-Vis spectroscopy and HPLC to analyze, quantify, characterize, and formulate protein conjugates. Contribute to the maintenance of laboratory infrastructure and equipment. Support group organization, productivity, and expertise through collaboration and idea exchange. Meet quality, quantity, and timeline expectations for all assigned projects. Support discovery efforts in protein sciences. Maintain accurate and complete electronic notebook records. Communicate experimental plans and data to multiple cross-functional scientific teams. BS/MS degree in biology, biochemistry, biophysics, chemistry, or a related field, with 0-1 years of relevant laboratory experience in a biopharma or academic setting. Familiarity with protein and/or antibody structure and function. Experience with protein binding techniches (ELISA, flow cytometry, SPR and/or BLI) preferred. Experience with instrumentation such as Octet, Biacore, flow cytometers, and UV-Vis spectrometeters preferred. Experience with protein and protein conjugate analysis (e.g., affinity chromatography, SEC, IEX, SDS-PAGE, UV-Vis spectroscopy) preferred. Experience with sterile technique and/or handling mammalian cell culture is a plus. Passion for driving projects from the bench, independently contributing to research goals, and solving challenging problems. Detail-oriented, self-motivated, and comfortable working on highly technical projects in a multidisciplinary team setting. Effective written and oral communication skills.
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