NGS Lab Scientist

You Will: 

• Prepare tissues and primary cells for single-cell suspension 

• Generate single‑cell immunoprofiling libraries using 10x Genomics workflows, including Gene Expression and TCR libraries 

• Utilize laboratory automation platforms to support and streamline library preparation workflows 

• Perform next‑generation sequencing using Illumina NovaSeq X Plus platforms 

• Optimize and troubleshoot assays to improve performance, including dead‑cell removal and T‑cell enrichment strategies 

• Design, execute, and support NGS‑based assays, working both independently and in cross‑functional teams 

• Contribute to data management and tracking using electronic laboratory notebooks (ELN) 

• Manage multiple priorities to meet project timelines while maintaining accurate experimental records and clear communication of results 

• Present findings and progress updates in internal and cross‑functional forum 

• Support additional activities as needed to advance broader team and organizational objectives 

You Have: 

• Five (5) years with BS/BA, or two (2) years with MS/MA in immunology, cellular or molecular biology or in a relevant discipline with related lab or industry experience 

• Background in genomics and molecular biology 

• Hands-on experience with NGS library preparation 

• Proficiency with single-cell NGS platforms (10X Genomics platform) 

• Experience with using Illumina sequencers (NovaSeq X Plus) 

• Experience with laboratory automation platforms for library preparation (10X Chromium Connect and/or Beckman Biomek i7 

• Experience with preparation of primary cells for single-cell suspension 

• Well-versed in cell culture aseptic techniques 

• Organizational and record-keeping abilities 

• Team-oriented attitude with the capability to work independently and in collaboration 

• Open to taking on temporary responsibilities beyond the initial job description 

Essential Qualifications, Skills and Experience 

• Bachelor’s degree (BS/BA) with at least five years, or Master’s degree (MS/MA) with at least two years of relevant laboratory or industry experience in immunology, cellular or molecular biology, or a related discipline. 

• Demonstrated hands-on experience with next-generation sequencing (NGS) library preparation and single-cell NGS platforms (e.g., 10x Genomics). 

• Proficiency in using Illumina sequencers (NovaSeq X Plus) and laboratory automation platforms (such as 10X Chromium Connect and/or Beckman Biomek i7). 

• Strong organizational and record-keeping skills, including experience with electronic laboratory notebooks (ELN). 

• Ability to manage multiple priorities, meet project timelines, and maintain accurate experimental records. 

• Effective communicator, able to present findings and progress updates in internal and cross-functional forums. 

• Team-oriented attitude with the capability to work independently and collaboratively. 

• Flexibility to take on temporary responsibilities beyond the initial job description. 

Technical & Scientific Expertise 

• Preparation of tissues and primary cells for single-cell suspension. 

• Generation of single-cell immunoprofiling libraries using 10x Genomics workflows, including gene expression and TCR libraries. 

• Optimization and troubleshooting of assays to improve performance, including dead cell removal and T-cell enrichment strategies. 

• Execution and support of NGS-based assays, both independently and as part of cross-functional teams. 

• Experience with cell culture aseptic techniques and preparation of primary cells for single-cell analysis. 

• Familiarity with laboratory automation platforms to streamline library preparation workflows. 

• Data management and tracking using ELN systems. 

Domain Experience 

• Background in genomics and molecular biology, with practical experience in clinical and commercial production environments. 

• Experience working with multi-omic data sets from clinical trials, supporting bioinformatic research efforts. 

• Exposure to Cell therapy and immunoprofiling applications, particularly within a clinical or translational research setting. 

• Understanding of operational workflows in a regulated laboratory environment, including compliance with quality standards.