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Postdoctoral Fellow, Vascularization

icon building Company : Biohub
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Job Description - Postdoctoral Fellow, Vascularization

Biohub is a 501(c)(3) biomedical research organization building the first large-scale scientific initiative combining frontier AI with frontier biology to solve disease. We build the technology to help scientists around the world use AI-powered biology to study how cells operate, organize, and work as part of systems to understand why disease happens and how to correct it. With our compute capacity, AI research and engineering, and state-of-the-art technology for measuring, imaging, and programming biology, we are enabling scientists worldwide to use AI-powered biology to advance our understanding of human health.

The Team


Our decoding inflammation team builds tools to enable precise molecular-level measurements of inflammation within human tissues in real time, and develop proactive, early interventions that can be deployed when inflammation — which underlies the most significant causes of death worldwide — first flares in the body. You can learn more about our work here


Our team collaborates with three powerhouse universities - Northwestern University, the University of Chicago, and the University of Illinois Urbana-Champaign - to develop first-in-class technologies and make breakthroughs.


Our Vision



  • Pursue large scientific challenges that cannot be pursued in conventional environments

  • Enable individual investigators to pursue their riskiest and most innovative ideas

  • Facilitate research by scientists and clinicians at our home institutions and beyond


We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease.


The Opportunity


We are seeking a Postdoctoral Fellow to join our Instrumented Tissues effort with a focus on organoid vascularization.


You’ll work independently on developing protocols to polymerize cell-laden hydrogel mixtures with 2-photon 3D printing. You will be interfacing with the rest of the team in order to create computational designs of the vasculature, create automation pipelines to tackle multi-scale printing and develop a robust vasculature forming biology. Your attention to detail, initiative, and relationship-building skills will directly contribute to our collective success.


What You'll Do



  • Develop state-of-the-art photopatternable hydrogel-cell mixtures

  • Optimize computational layout of vasculature with inlet, outlet, and branching statistics

  • Create surrounding support environmental chambers (3D printing, CNC, etc) compatible with 2-photon 3D printing

  • Characterize fidelity of vasculature via fluorescence microscopy

  • Cultivate primary cells from endothelium


What You'll Bring



  • PhD in Biomedical Engineering, Biology or related field

  • Three years of experience in vasculature biology including primary cell culture

  • Three years of experience in advanced microscopy

  • Strong understanding of prototype engineering (printing, milling, automation).

  • Ability to use simulation tools (Python)  to improve vasculature design.


Compensation


The Chicago, IL base pay for a new hire in this role is $84,150. 


Benefits for the Whole You 


We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible. 



  • Provides a generous employer match on employee 401(k) contributions to support planning for the future.

  • Paid time off to volunteer at an organization of your choice. 

  • Funding for select family-forming benefits. 

  • Relocation support for employees who need assistance moving


If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.


#LI-Onsite

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