Postdoctoral Researcher Position: iPSC Bioprocess Development

Overview

The Terasaki Institute for Biomedical Innovation develops personalized therapeutic solutions using advanced micro- and nanoscale technologies to address major challenges in organ failure, cardiovascular disease, and cancer. Working closely with clinicians and translational partners, the Institute advances stem cell engineering, biomaterials, and biofabrication platforms toward clinical translation.

We are seeking a highly motivated Postdoctoral Researcher with expertise in human iPSC expansion and dynamic suspension culture to develop scalable stem cell manufacturing workflows using vertical-wheel bioreactor systems.

Key Responsibilities

• Establish and optimize human iPSC expansion in vertical-wheel bioreactor systems.


• Control aggregate formation, size distribution, and uniformity.


• Optimize agitation rate, oxygen transfer, feeding strategies, and media exchange protocols.


• Develop scalable workflows for high-density suspension culture.


• Perform analytical characterization including flow cytometry, qPCR, and immunostaining.


• Collaborate with stem cell differentiation and biomaterials teams.

Required Qualifications

• PhD. in Biomedical Engineering, Chemical Engineering, Stem Cell Biology, or related field.


• Hands-on experience with human iPSC culture.


• Experience with suspension culture systems or bioreactors.


• Strong analytical and troubleshooting skills.

Preferred Qualifications

• Experience with vertical-wheel bioreactors.


• Knowledge of oxygen transfer dynamics and metabolic monitoring.


• Experience scaling stem cell cultures beyond small laboratory formats.

Application Materials

• Curriculum Vitae (CV).


• 1–2 page research statement detailing bioreactor and stem cell experience.


• Contact information for three professional references.