We are hiring a creative Principal Engineer, Automation to join our incredible team at Verve Therapeutics, Inc. in Boston, MA.
Growing your career as a Full-Time Principal Engineer, Automation is an awesome opportunity to develop key skills.
If you are strong in research, project management and have the right mindset for the job, then apply for the position of Principal Engineer, Automation at Verve Therapeutics, Inc. today!
The Company
Verve Therapeutics is a biotechnology company created with a singular focus: to protect the world from heart disease. Founded by world-leading experts in cardiovascular medicine, human genetics and gene-editing, the company aims to develop transformative, once-and-done therapies for coronary heart disease. Verve's gene editing medicines are designed to safely edit the genome of adults and mimic naturally occurring gene variants to permanently lower LDL cholesterol and triglyceride levels. The company is advancing a pipeline of precision genetic medicines, led by VERVE-101, which is being developed initially for heterozygous familial hypercholesterolemia, a potentially fatal genetic heart disease. In 2023, Verve was named a Top Place to Work by The Boston Globe for the third consecutive year. Verve is headquartered in Boston, Massachusetts.
The Position
Verve is seeking a Principal Engineer to lead the Automation team. The automation team at Verve collaborates cross-functionally to build bespoke automated solutions for a variety of workflows spanning gene editing, analytical and next generation sequencing. This is a great opportunity for a skilled and collaborative individual to develop and manage high impact automation projects which will enable Verve on its mission of developing safe and efficient precision medicines.
Job Responsibilities
- Lead an in-house automation team to implement automation across the company to increase efficiency, standardization, and throughput of NGS workflows
- Develop near-, mid-, and long-term strategies to automate various processes across different R&D groups, including NGS, Analytical Development, RNA Technology teams and more
- Work closely with cross-functional teams, including, scientists, engineers, and IT professionals to identify opportunities for automation and ensure successful implementation of automation systems
- Oversee the implementation of automation systems, including selecting appropriate hardware and software, configuring systems, testing and troubleshooting, and providing training to end-users
- Manage automation projects from conception to completion, ensuring that projects are completed on time, within budget, and meet the desired objectives
- Stay up to date with the latest developments in automation technology and industry best practices to ensure that Verve are at the forefront of automation innovation
- Ensure that data generated using automation is accurate, reliable, and auditable and of the highest quality
- Work with others in the automation team to script new methods, integrate hardware and optimize existing methods to enable high-throughput solutions used by internal teams.
- Manage a fleet of liquid handling platforms, including creating SOPs, maintaining fleet health and scheduling preventative maintenance.
- Work closely with Computational Biology, Quality Assurance, Quality Control, Information Technology, and Regulatory groups to ensure conformance of automation workflows with regulatory requirements as appropriate
- Demonstrate exceptional time management skills and drive to support automation adoption and increase data output
- Other duties as assigned
Qualifications
- PhD in life sciences or engineering field with 6+ years of relevant industry experience with demonstration of successful implementation of automation workflows
- or M.S in life sciences or engineering field with 8+ years of relevant industry experience
- or B.S. in life sciences or engineering field with 12+ years relevant industry experience
- Experience implementing automation in genomics and NGS workflows is highly preferred
- Strong technical background and familiarity with a wide range of automation technologies, including hardware and software systems, control systems, robotics, and data analytics
- Previous experience with liquid handling platforms, laboratory automation equipment including Hamilton, Tecan, and Agilent based systems is required.
- Demonstrate advanced programming expertise with commercial liquid handlers and HTS software is required (Venus on Vantage, Fluent Control, and VWorks)
- Experience implementing fully automated, end-to-end automation solutions, such as High Res Bio Systems or Biosero is desirable
- Experience with and operational knowledge of immunoassay/ELISA based instruments such as flow cytometers, MesoScale, BioTek, Cytomat, and Multi-mode plate readers
- Programming knowledge in .NET (VB, C#, ASP), Python, Java Script, SQL server, VBA Excel and Matlab are highly desired
- Strong familiarity with the gene therapy development and discovery process
- Experience leading a team of engineers and mentoring them as they progress in their careers
- Excellent analytical and problem-solving skills, with the ability to identify and solve complex problems
- Effective communicator with the ability to explain technical concepts to non-technical stakeholders and collaborate with cross-functional teams effectively
EEO Statement
Verve Therapeutics is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.
Recruitment & Staffing Agencies
Verve Therapeutics does not accept agency resumes unless contacted directly by internal Verve Talent Acquisition. Please do not forward resumes to Verve employees or any other company location; Verve Therapeutics is not responsible for any fees related to unsolicited resumes.
Benefits of working as a Principal Engineer, Automation in Boston, MA:
● Opportunity to Make a Difference
● Continuous Learning Opportunities
● Attractive packageCompetitive Pay
No CV Required
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