Principal Statistical Programmer

Develop and follow good programming practices, including adequately documenting SAS and R code; Perform, plan and coordinate project work to ensure timely, quality delivery across multiple projects; Create and validate global macros or systems that streamline repetitive operations to increase programming efficiency; Keep abreast of current and new statistical programming techniques and other applicable technical advancements while assisting in their implementation; Provide input into, or lead general standardization efforts (e.g., CRFs, query checks, standard statistical programs, data presentations); Assist or lead efforts to develop programming processes consistent with industry best practices; Review DMP, eCRF specs, and other clinical data management documents; Review statistical analysis plans and other related documents; Partner with or oversee CROs or Programming vendors to perform any of the above tasks; At least 8 years' industry (Pharmaceutical, Biotech, CRO) SAS programming experience or equivalent; Knowledge of clinical trials and experience in using SAS to report the results of clinical trials and/or integrated analysis for submission; Experience in constructing technical programming specifications and producing complex, validated programs; Strong experience in working with CDISC standards, including SDTM, and ADaM, and Define xml; Excellent knowledge of SAS Macro, SAS/SQL, SAS/GRAPH, and SAS/STAT; Clear alignment with Alnylam Core Values: Commitment to People Innovation and Discovery Sense of Urgency Open Culture Passion for Excellence