Research Associate I/II Clinical Pathology/IHC Biomarker Development

Salary :

$60,000 - 80,000 yearly

Company : Systimmune

Job Type : Full Time

Redmond, Wa

Number of Applicants

000+

Let AI Supercharge Your Job Hunt!

JobCopilot scans 500,000+ company career sites daily to find jobs for you

Never miss an opportunity Save hours by auto-filling applications forms Land more interviews with tailored applications

Activate JobCopilot

Job Description - Research Associate I/II Clinical Pathology/IHC Biomarker Development

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ. It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs). SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications. Alongside ongoing clinical trials. SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development. We offer an opportunity for you to learn and grow while making significant contributions to the company's success.

We are seeking a highly organized and detail-oriented Research Associate I/II to support the development, optimization, and validation of immunohistochemistry (IHC) assays. This role will contribute to early-stage biomarker in support of clinical trial programs.

The ideal candidate will have 2–3 years of hands-on industry experience in histology, IHC, or a regulated laboratory environment (e.g., CLIA/CAP, GLP). This is a bench-focused position requiring close collaboration with scientists, pathologists, and cross-functional project teams.

Key Responsibilities
Histology

Perform tissue sectioning of FFPE blocks.
Route and support H&E staining workflows.

IHC Assay Execution

Perform routine IHC staining on FFPE tissue specimens using automated platforms (e.g., Ventana, Leica).
Conduct antibody titrations, protocol optimization, slide preparation, and quality control checks.
Assist in generating feasibility, optimization, and analytical validation data for emerging CDx assays.
Experience with Akoya PhenoImager HT platforms is preferred.

Sample & Workflow Support

Manage tissue samples and associated documentation.
Prepare tissue sections, including slide cutting, baking, antigen retrieval, and reagent preparation.
Maintain sample integrity, traceability, and documentation in compliance with quality system requirements.
Support tissue handling workflows (blocks, slides, labeling, storage) within GLP or CLIA/CAP environments.

Data Collection & Documentation

Accurately record experimental data in ELN and/or LIMS systems.
Capture high-quality slide images and perform basic image analysis.
Assist with slide scoring preparation and data summaries.
Summarize experimental findings for internal meetings and assay development reviews.

Instrument & Laboratory Maintenance

Operate, calibrate, and troubleshoot automated IHC staining platforms and related laboratory equipment.
Perform routine instrument maintenance and maintain equipment logs per laboratory quality systems.
Monitor and manage inventory of reagents, antibodies, controls, and consumables.

Cross-functional Support

Collaborate with scientists, pathologists, QA, and clinical development teams on assay transfer, optimization, and validation activities.
Support preparation of study materials, controlled documents, and protocol execution for validation studies.

Qualifications

BS or MS in Biology, Molecular Biology, Pathology, Biomedical Sciences, or a related field.
1–3 years of hands-on experience in histology and/or IHC assay execution within a research or regulated diagnostic laboratory.
Experience handling FFPE tissues and operating automated IHC staining platforms.
Strong attention to detail with excellent documentation and record-keeping practices.
Ability to follow SOPs and work effectively in CLIA-, GxP-, or ISO-regulated environments.

Preferred

Experience supporting IHC assay optimization and/or analytical validation studies.
Exposure to Akoya platforms and multiplex immunofluorescence projects.
Experience with digital pathology, slide scanning, or image analysis tools.
Knowledge of antibody characterization and tissue-based biomarker assay development.

Compensation and Benefits:
The expected base salary range for this position is $60,000 - $80,000 annually. Actual compensation will be based on a variety of factors, including but not limited to a candidate’s qualifications, experience, and skills.
While most offers typically fall within the low to mid-point of the range, we may extend an offer toward the higher end for exceptional candidates whose background and expertise exceeds the requirements of the role.

SystImmune is a leading and well-funded biotech company with a bright future. We offer an opportunity for you to learn and grow while making significant contributions to the company’s success. SystImmune offers a comprehensive benefits package including: 100% paid employee premiums for medical/dental/vision, also STD, LTD, a 401(k) plan with a 50% company match of up to 3% and a vesting schedule of only 5 years, 15 PTO days per year, sick leave, plus 11 paid holidays and MORE.

We offer an opportunity for you to learn and grow while making significant contributions to the company’s success.

SystImmune is an Equal Opportunity Employer. We welcome diverse talent and encourage all qualified applicants to apply.

Original job Research Associate I/II Clinical Pathology/IHC Biomarker Development posted on GrabJobs ©. To flag any issues with this job please use the Report Job button on GrabJobs.

Auto-Apply to Similar Jobs

Share Job

Get your Resume Reviewed for Free

Automate Job Applications for Similar Jobs

Auto-Apply to Research Associate I/II Jobs with your AI JobCopilot

Auto-Apply with AI

Similar Research Associate I/II Jobs in the US

Get your Resume Reviewed for Free

Email address

Why are you reporting this job?

I think it’s a discriminatory or offensive

I think it’s fraudulent or a scam

I think it’s trying to sell something unrelated to the job / it’s asking for money

I think it contains incorrect or broken information

Other

All Job Ads are subject to GrabJobs’s Terms of Service. We allow users to flag postings that may be in violation of those terms. Job Ads may also be flagged by GrabJobs moderation team. However, no moderation system is perfect, and flagging a posting does not ensure that it will be removed.

Setup your job alert:

Frequency

By activating job alerts, I agree to GrabJobs Terms & Privacy Policy. I can unsubscribe to job alerts anytime. Skip

Research Associate I/II Clinical Pathology/IHC Biomarker Development

Job Description - Research Associate I/II Clinical Pathology/IHC Biomarker Development

Similar Research Associate I/II Jobs in the US

Mobile Apps