Research Scientist Nucleic Acids Chemistry R&D

Centrillion is creating transformative genomic technologies leveraging engineering and biochemistry breakthroughs to accelerate discovery and reveal the real genome that has thus far been obscured by its complexity and the limitations of existing technologies. Our team of scientists and engineers is committed to making a new generation of genomic technologies accessible and affordable for a multitude of previously unapproachable apps. Centrillion is backed by venture capital and strategic investors and is located at Palo Alto, CA, at the innovation center of Silicon Valley and close to Stanford University.

Centrillion Biosciences is seeking a creative, energetic, resourceful organic chemist to join a multidisciplinary research team developing new technologies for nucleic acid sequence analysis.

Duties:

• Plan and execute applied research experiments involving:
• Synthesis, modification and characterization of modified nucleotides, nucleoside polyphosphates and oligonucleotides
• Preparation of fluorescent dye conjugates of nucleotides and oligonucleotides.
• Materials modification and characterization for solid phase synthesis 
• Collaborate with and/or supervise other scientists & engineers on joint projects.
• Documentation of experimental work; analysis of data; documenting and presenting results
• Preparation of written methods and SOPs 
• Operation and maintenance of laboratory & analytical equipment 
• Support R&D and Pilot Manufacturing Operations and QC 

• PhD in organic chemistry, with extensive training and practical laboratory experience in organic synthesis, physical organic and bioorganic chemistry.
• Experience with nucleoside, nucleotide, and solid-phase oligonucleotide synthesis.
• Experience preparing fluorescent dye conjugates of nucleotides and oligonucleotides.
• Proficiency in the use of methods of instrumental chemical analysis, such as NMR, HPLC, MS, FTIR, is essential.
• Working knowledge and practical experience with polymer and surface chemistry is strongly desired.
• Demonstrated ability to plan and execute independent and collaborative research projects. 
• Demonstration of goal-oriented, hands-on and innovative approach to problem solving.
• Excellent written and oral communication skills.
• Co-authorship on one or more publications in peer-reviewed scientific journals.
• She/he will be required to develop additional competencies, and apply practical skills and knowledge to solving a variety of applied scientific and technical problems.

All your information will be kept confidential according to EEO guidelines.