Research Technician II

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You.

The Global Health Discovery Collaboratory (GHDC) Antibody Dynamics team at the Duke University Center for Human Systems Immunology is seeking a detail-oriented scientist to fulfill a key role as Research Technician II to support assessment of antibody biophysical measurements in an immune monitoring core lab. The assays performed by the Research Technician II include bio-layer interferometry and surface plasmon resonance methods to assess the antigen binding kinetic measurements of antibodies induced by vaccination in human clinical and pre-clinical vaccine trials for HIV, malaria, tuberculosis and other high priority global diseases

Minimum Requirements:

•         Bachelor’s degree in Biochemistry, Biophysics or related Biological Science field.

Preferred Qualifications:

• Master’s degree in a related Biological Science field is a plus. 


• Prior biochemistry or biophysics or biological laboratory experience.


• Experience in using SPR or BLI is a plus.


• Experience in working on R studio and/or Mathematica is a plus

Other Requirements:

This position is onsite. The work is performed on-site or at a designated assignment location.

Be Bold.

Responsibilities

• Perform experiments to measure biomolecular interactions (i.e. binding kinetics and affinity) utilizing Surface Plasmon Resonance (SPR) and/or Bio-layer interferometry (BLI).


• Manage, track, and analyze data sets related to the evaluation of antibody responses to vaccines for human studies.


• Work together with the program manager, statistical team and laboratory staff ensure quality control of datasets.


• Work with the Quality Assurance Unit to maintain and perform work according to Good Clinical Laboratory Practices


• Collaborate with team members to develop custom tools for high throughput analysis of complex data sets.


• Perform other related laboratory duties as assigned by the Principal Investigator.

Choose Duke.

Join our award-winning team and be part of an inclusive culture that is committed to providing outstanding patient care, training tomorrow’s leaders, and conducting innovative research. You'll also benefit from Duke's competitive benefits package, including health insurance plans, generous paid time off, retirement programs with employer contributions, tuition assistance for employees and their children, and more.