Scientist

Pleased to meet you, we are Galapagos, a dynamic growing Biotech company with offices across Europe and in US, headquartered in Mechelen, Belgium.

We are in the business of changing lives. Focusing on high unmet medical needs, we synergize compelling science, technology, and collaborative approaches to create a deep pipeline of best-in-class medicines. With capabilities from lab to patient, including a decentralized cell therapy manufacturing platform, we are committed to challenging the status quo and delivering results for our patients, employees and shareholders. Our goal is not just to meet current medical needs but to anticipate and shape the future of healthcare, ensuring that our innovations reach those who need them most.

We pioneer for patients. We need thought leaders and rapid thinkers, entrepreneurs in spirit and status quo-fighters. Collaborative innovators and perseverant idealists. We need the best-in-class. In other words, we need you: The ‘make-it-happener’.

We are looking for a Scientist CAR-T to join one of our stellar CAR-T Discovery teams in Pittsburgh. You are a creative researcher with a strong track record in experimental design, execution and troubleshooting. In this role, you will contribute to an array of innovative, early-stage projects at the cutting edge of immuno-oncology research and discovery and development of antibody-based therapeutics.

Your role

Your primary responsibilities will include but are not limited to:

• Lead projects. Facilitate idea gathering and problem-solving, and coordinate deadlines and priorities.

• Design and generate phage-display antibody libraries independently or with senior team members.

• Discover antibodies through panning and screening phage-display libraries.

• Engineer antibodies using molecular cloning techniques.

• Characterize antibody candidates via biophysical, biochemical, immunological, and cell-based bioassays.

• Design, generate, and characterize bispecific antibodies, ADCs, and CAR-T cells.

• Elucidate anti-tumor mechanisms of antibody candidates in vitro and in vivo.

• Interpret experimental data, draw conclusions, present results, and participate in lab meetings.

• Draft patent applications and manuscripts for publication.

• Maintain records according to SOPs and policies.

Who are you?

• You obtained your PhD in Life Sciences, focusing on Cell Therapy with a specialization in CAR-T research, or have built significant experience in CAR-T post-PhD. Publications in prestigious journals are a plus.

• Experience in cell proliferation, cytotoxicity assays, lentiviral vector design and CAR-T cell generation. Any experience related to arming or modifying the metabolic pathway for improving in vivo CAR-T efficacy is a plus.

• Ability to work independently and juggle multiple responsibilities simultaneously.

• Hard-working and interested in learning advanced laboratory techniques and new experimental procedures.

• Critical thinker with an investigative attitude. You like to solve complex problems.

• Good collaborator and honest, clear communicator.

• Based in the Pittsburgh area as this is an on-site, lab-based position.

What’s in it for you?

At Galapagos, we prioritize your continuous growth and development, fostering a culture of empowerment. Our employees are the driving force behind our mission to lead in pharmaceutical research and innovation.

Base compensation for this position ranges from $81,000 to $135,000. Actual base compensation will be determined based on a variety of factors including experience, qualifications, job-related knowledge, demonstrated skills and geographic location. The company reserves the right to modify base salary ranges at any time.

In addition, this position is eligible for participation in Galapagos’ performance bonus plan. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support important moments in life.

Galapagos is dedicated to ensuring equal employment opportunities. Our hiring decisions are based on merit, considering qualifications, skills, performance, and achievements. We strictly prohibit discrimination against any employee or job applicant based on personal characteristics that are unrelated to their job.

We are Galapagos: together, we make it happen…!