Scientist

37099280 Scientist III Ridgefield , CT 24 Months

Sigma Systems is currently looking for a Scientist.

Responsibilities:

• Join the Immunology & Respiratory Department's Discovery Sciences Team to identify and develop transformational drugs for immune-mediated diseases.
• As in vitro scientist, you will work closely with the project leader and in vitro lead to develop, validate, and execute assays to modulate lymphocytes.
• Work closely in a matrix global team to meet project achievements, with the goal to deliver therapies that transform the lives of patients.
• As in vitro scientist on projects, you will design and execute in vitro assays for target validation, compound profiling and hit validations.
• Work closely with project lead and in vitro lead to deliver high quality assays.
• Interact with other scientists in the group to share assay protocols and seek feedback on assay design and troubleshooting.
• Maintain accurate and reliable records including electronic notebooks and all other pertinent documentation.
• Present data at project team meetings and group meetings

Requirements:

• Master's degree from an accredited institution with one-plus (4+) years of experience in a related scientific discipline (Biology, Immunology, Cell biology) OR Bachelor's degree from an accredited institution with seven-plus (7+) years of experience in a STEM discipline.
• Prior experience working in pharma or equivalent industry is not required but will be considered a plus.
• Prior experience with establishing and validating in vitro assays for lymphocyte functions and modulations (B and T cells) is desired.
• Experience in gene knockdown, CRISPR, validation is desired but not necessary
• Experience in immune phenotyping and functional assays, including multicolor flow cytometry (10+ colors), ICS, ELISpot, proliferation assays, and cytokine ELISA/MSD.
• Analyzing data using biological and statistical software such as Prism, FlowJo, OMIQ, Excel, etc.