Scientist I, Cellular Biology/In Vitro Immunology

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

We are looking for a highly motivated scientist to join our Gastroenterology team in Discovery Research Immunology located in Cambridge, MA.  The ideal candidate should be independently driven, highly collaborative, and results oriented.  They will support in vitro efforts for our existing early-stage through late-stage discovery portfolio programs.  Responsibilities include planning, conducting, and analyzing in vitro assays as well as present data findings to explore key biological questions related to IBD.  The candidate should be proficient in basic laboratory techniques including substantial experience with primary human cells.

Responsibilities:

• Develop, optimize, and implement new methods/techniques as needed to generate reliable and reproducible data for new projects and biological questions in a timely manner.
• Develop cell-based functional assays using cell lines, human primary cells, and mammalian blood/tissue-derived cells
• Conduct functional assays, including immune cell activation, differentiation and immuneprofiling, that further project goals
• Perform advanced molecular biology and cellular biology techniques (qPCR, flow cytometry, ELISA, MSD, HTRF)
• Isolate immune cells from relevant human and mouse blood and tissues
• Work independently on the design, execution and interpretation of experimental results to validate hypotheses and help advance target identification and validation within GI immunology
• Analyze, interpret, document and present data concisely and rigorously, both to individual stakeholders and in group settings.
• Demonstrate scientific excellence through dedication to multiple projects in a fast-paced multi-disciplinary environment
• Literature review for insights that aid experimental design and contribute ideas
• Impact projects mostly through wet lab-based activities.  This position is expected to be on-site 90% of the time with 10% dedicated to lab notebook and study design.
• Maintain organized electronic lab notebook of all study data and records.

Qualifications:

• B.S. or M.S. in Immunology, Cell biology, or in a related discipline with expertise in immunology research, with typically 5+ (BS) or 2+ (MS) years of job-related experience.
• Experience in in vitro human cell culture including various types of immune cells, and cell-based assay development is required.
• Experience in human cell profiling by flow cytometry is required.
• Experience in immunoassays using techniques like qPCR, ELISA, MSD and/or HTRF is required.
• Experience in small molecule or biologic screening in human cells is preferred.
• Experience in microscopy, organoid culture, and mammalian tissue ex vivo processing is preferred
• Ability to learn new skills and apply them in a fast-paced research environment is a must.
• Creativity, problem-solving, and attention to details are required.
• Excellent oral and written communication and collaboration skills are required.
• Ability to work independently as well as in a team is a must.
• Proven flexibility to deal with changing timelines and shifting work priorities.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​​

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• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​​

• This job is eligible to participate in our short-term incentive programs. ​​

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Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

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