Senior Analyst, IT - Duke Cancer Institute

School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Be You.

The Duke Cancer Institute is seeking a Senior Analyst, IT to join a high-impact team supporting enterprise clinical analytics, Electronic Health Record (EHR) optimization, and large-scale workflow transformation initiatives.

In this role, you will serve as a strategic partner to clinical, operational, and technical teams—helping translate complex data, workflow, and reporting needs into practical, scalable solutions. You’ll work with limited supervision and a high degree of autonomy, leading initiatives that require strong analytical skills, systems thinking, and structured change management.

A major focus of this position is supporting the electronic Patient Reported Outcomes (ePRO) PCORI Health System Implementation Initiative (HSII), including implementation of the Epic eSym module across approximately 45 clinics. You will play a critical role in coordinating cross-functional teams, redesigning clinical workflows, developing training and support materials, and driving adoption of new tools across diverse clinical environments.

If you enjoy working at the intersection of data, technology, and clinical operations—and want to help drive meaningful improvements in care delivery—this role offers the opportunity to make a system-wide impact.

Minimum Requirements

• Bachelor’s degree in a relevant field, including but not limited to:

• Health Informatics


• Information Technology / Information Systems


• Industrial Engineering


• Computer Science


• Data Analytics / Data Science


• Public Health


• Healthcare Administration


• Nursing or other clinical discipline with informatics experience

• 3–5 years of relevant experience, including:

• Data analytics, reporting, or informatics work


• Experience working with Electronic Health Records, preferably Epic


• Exposure to healthcare or clinical environments

Preferred Qualifications

• Master’s degree strongly preferred (Health Informatics, Data Analytics, Public Health, Healthcare Administration, Business Administration, Nursing Informatics, or related field)


• 5+ years of progressive experience supporting or leading complex, cross-functional initiatives


• Demonstrated experience with:

• Clinical workflow analysis and redesign


• Change management for system or process implementations


• Grant-funded or large-scale health system initiatives


• Development and delivery of end-user training


• Translating technical solutions into operational practice

Other Requirements

• This position is hybrid eligible.

Be Bold.

You will:

• Partner with clinical, operational, and technical teams to understand EHR data, analytics, and workflow needs; gather requirements and translate them into technical, analytical, and process-based solutions.


• Lead and support EHR-related change initiatives, particularly those involving Epic enhancements, ePRO implementation, and clinical workflow transformation.


• Analyze current-state clinical workflows and design future-state workflows to support new systems and operational improvements in clinic settings.


• Design and implement analytical and operational solutions where none currently exist, including development of new processes, workflows, and support models.


• Determine optimal methods to collect, store, integrate, retrieve, and analyze data from multiple sources across health system platforms.


• Serve as a subject matter expert for assigned teams by applying deep knowledge of analytics assets, EHR functionality, informatics tools, and reporting solutions.


• Apply structured change management methodologies to support adoption of new tools, workflows, and processes across clinical environments.


• Coordinate and execute complex projects with minimal direction, ensuring milestones, deliverables, and deadlines are met.


• Contribute expert input during project initiation, including guidance on clinical workflows, data sources, data elements, and relationships across systems.


• Perform quality assurance testing and validation of analytical, reporting, and operational solutions; assess results and implement corrective actions prior to production deployment.


• Ensure compliance with departmental standards, including change management processes, naming conventions, documentation requirements, and maintenance of the enterprise reporting library.


• Write, maintain, and document code and technical solutions supporting analytics, reporting, and operational workflows.


• Develop and deliver training programs for clinic staff related to EHR enhancements, informatics tools, and workflow changes—including patient-facing education related to electronic patient reported outcomes.


• Serve as a liaison between clinical, operational, and technical stakeholders, clearly communicating needs, risks, status updates, and solutions.

Choose Duke.

At Duke Health, you’ll be part of a collaborative and mission-driven organization committed to excellence, discovery, and improving patient lives through innovation. Our teams support nationally recognized research, clinical care, and grant-funded initiatives that shape the future of healthcare delivery.

Job Code: 00002426 ANALYST, IT, SR

Job Level: D

Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions:

Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.