Senior Associate Scientist, DMPK

Assist in assay optimization and qualification of in vitro DMPK assays across technologies in cell free or cell culture systems Assist in assay optimization and qualification of safety pharmacology experiments to assess the safety of RNAi therapeutics for early and late-stage development Perform non-GLP sample analysis to support all Alnylam's RNAi therapeutics development from early to late stage Use scientific literature and scientific knowledge to improve experimental design and inform project direction. Maintain appropriate procedures and controls to ensure consistent assay performance and reproducible data Maintain high quality documentation, perform data analysis and monitor performance of Quality Controls. Learn in-depth knowledge about the technologies and platforms used to generate results to help troubleshoot, address queries, and present data to diverse groups within Research and Development. Collaborate cross-functionally and represent DMPK group Research and implement new technologies to improve assay performance, quality, and efficiency. A Master's degree (3+ years of pharmacokinetic assays bench-work experience) or Bachelor's degree (5+ years of pharmacokinetic bench-work experience) in biology, pharmaceutical sciences, biochemistry, chemistry, or relevant field. Hands-on molecular bench-work experience (MSD, LCMS/MS, ELISA) Must have experience with Excel, Word, and PowerPoint. Experience with other analytical software is a plus (e.g. Phoenix, GraphPad Prism, Discovery Workbench). Detail-oriented with the ability to thrive in a team environment and be comfortable working on multiple projects. Meticulous and diligent at record keeping and organizing experiment files to be readily accessible to the team Possesses excellent interpersonal, verbal and written communication skills to enable collaboration with cross-functional teams