Senior Associate Scientist, Process Sciences

Design and conduct laboratory experiments, analyze results, and draw meaningful conclusions. Support downstream processing method optimization. Execution of oligonucleotide downstream processes to provide the research and in-house non-GMP material in a tight timeline. Execution of in-process analytical tests. Participate in creating and reviewing SOPs and batch records in support of the in-house non-GMP manufacture. Oligonucleotide manufacturing, process development, optimization and scale up. Operation and optimization of downstream processing. Manufacturing of oligonucleotide APIs in a cGLP environment. Operation of analytical instruments and application of analytical techniques. BS in Chemical Engineering or Chemistry with a minimum of 2 years lab experience, preferably in an industrial setting. Basic understanding of analytical techniques (pH, osmolality, conductivity measurement, HPLC, LC-MS etc.). Related hands-on experience is preferred. Knowledge of oligonucleotide manufacture process including phosphoramidite chemistry, chromatography, ultrafiltration etc. is a plus. Experience in record-keeping and excellent laboratory documentation practice, are required. Strong commitment to high laboratory and scientific standard.