Senior Director, Clinical Operations

Company : Vitalief

Job Type : Full Time

Philadelphia, Pa

Number of Applicants

000+

Let AI Supercharge Your Job Hunt!

JobCopilot scans 500,000+ company career sites daily to find jobs for you

Never miss an opportunity Save hours by auto-filling applications forms Land more interviews with tailored applications

Activate JobCopilot

Job Description - Senior Director, Clinical Operations

About Vitalief
Vitalief is a consulting and professional services firm that helps clinical research sites, sponsors, and CROs improve trial activation, operational performance, and workforce readiness. Our approach combines clinical research expertise, operational excellence, and business acumen to help teams do more with less. We enable clients to streamline processes, save time, reduce costs, accelerate results, and ultimately enhance patient outcomes.

The Role
Vitalief is partnering with a nationally recognized Academic Medical Center to recruit a Senior Director, Clinical Operations as a full-time, permanent member of the client’s leadership team. This role provides enterprise-wide leadership for the strategic direction, governance, and operational excellence of the institution’s clinical research portfolio. Reporting to executive leadership, the Senior Director oversees the full lifecycle of clinical research operations—from feasibility and study activation through closeout—ensuring alignment with institutional strategy, regulatory requirements, and long-term financial sustainability.

This leader is accountable for building and scaling a best-in-class clinical research infrastructure that supports investigator-initiated, industry-sponsored, and federally funded (NIH) research. The role emphasizes executive partnership, performance accountability, inspection readiness, and service excellence across a complex, matrixed academic environment.

Salary Range: Market competitive, commensurate with experience

Work Location: Philadelphia, PA (100% on-site)

Key Responsibilities

Enterprise Strategy & Governance: Provide executive leadership and governance for clinical research operations, aligning strategy, infrastructure, and performance with institutional priorities and regulatory expectations.
Clinical Research Portfolio Oversight: Oversee a complex, multi-therapeutic clinical trial portfolio, ensuring studies meet enrollment, timeline, budget, quality, and compliance standards.
Organizational Leadership & Talent: Lead and develop a large, multidisciplinary, and matrixed clinical research workforce, establishing clear accountability, competency frameworks, and succession planning.
Quality, Compliance & Inspection Readiness: Maintain enterprise-wide responsibility for regulatory compliance, quality systems, audit management, and sustained inspection readiness.
Financial Stewardship & Resource Optimization: Provide oversight of budgets, staffing models, and resource allocation to ensure scalable, financially sustainable research operations.
Growth & External Engagement: Advance institutional research growth through industry partnerships, NIH competitiveness, and external representation with sponsors and peer AMCs.

Qualifications

Advanced degree in a health, biomedical, or life sciences discipline (e.g., MD, DO, RN, PharmD, PhD, MPH, MS), or equivalent combination of education and executive clinical research experience
10 to 15 years of progressive clinical research experience, including senior leadership responsibility within an academic medical center or similarly complex research environment.
Demonstrated success leading enterprise or department-wide clinical research operations across multiple funding sources (industry and federal).
Expert knowledge of clinical research regulations and oversight frameworks (FDA, ICH‑GCP, OHRP, NIH, HIPAA, IRB).
Proven ability to design and scale clinical research infrastructure, SOPs, governance models, and quality systems.
Strong financial and operational acumen, including budget oversight, staffing strategies, and performance metrics.
Executive-level leadership skills with the ability to influence across matrixed organizations and communicate effectively with C‑suite and external stakeholders.

PHYSICAL DEMANDS: Prolonged periods sitting working on a computer, standing, walking, visual perception, talking and hearing. Lifting up to 20lbs.

Original job Senior Director, Clinical Operations posted on GrabJobs ©. To flag any issues with this job please use the Report Job button on GrabJobs.

Auto-Apply to Similar Jobs

Share Job

Get your Resume Reviewed for Free

Automate Job Applications for Similar Jobs

Auto-Apply to Senior Director, Clinical Operations Jobs with your AI JobCopilot

Auto-Apply with AI

Similar Senior Director, Clinical Operations Jobs in the US

Get your Resume Reviewed for Free

Email address

Why are you reporting this job?

I think it’s a discriminatory or offensive

I think it’s fraudulent or a scam

I think it’s trying to sell something unrelated to the job / it’s asking for money

I think it contains incorrect or broken information

Other

All Job Ads are subject to GrabJobs’s Terms of Service. We allow users to flag postings that may be in violation of those terms. Job Ads may also be flagged by GrabJobs moderation team. However, no moderation system is perfect, and flagging a posting does not ensure that it will be removed.

Setup your job alert:

Frequency

By activating job alerts, I agree to GrabJobs Terms & Privacy Policy. I can unsubscribe to job alerts anytime. Skip

Senior Director, Clinical Operations

Job Description - Senior Director, Clinical Operations

Similar Senior Director, Clinical Operations Jobs in the US

Mobile Apps