Senior Manager, CGT Operations Business Process

Job Description

About Vertex:

At Vertex, we are relentless in our pursuit of transformative medicines to improve the lives of people with serious diseases. Our Global Heme Cell and Gene Therapy (CGT) Operations team is at the forefront of innovation, commercial strategy, and operational excellence, driving the evolution of the global, cross-functional, "vein to vein” business process for CASGEVY, the only CRISPR-based autologous gene therapy approved for people living with Sickle Cell Disease and Transfusion dependent beta thalassemia.

Position Summary:

We are seeking a Senior Manager, CGT Operations Business Process to lead global business process initiatives for CASGEVY.  This critical role will collaborate cross-functionally to design and own the end-to-end process, essential to delivering a vein-to-vein, autologous product.  As CASGEVY continues to scale across 9+ markets globally, the successful candidate will drive process optimization and operational excellence cross-functionally in a GxP-regulated environment.

Key Responsibilities:

• Lead the evolution of the Global end-to-end (E2E) process by identifying and addressing improvement areas and process gaps in collaboration with stakeholders across commercial, quality, systems, and manufacturing, spearheading workstreams to design and implement changes to increase efficiency and drive strategic priorities
• Own and evolve global documentation leveraged by stakeholders across all markets and functions to ensure alignment, including business process maps, standard operating procedures, and other GxP materials
• Manage cross-functional forums to advance business process initiatives, gather insights, and problem-solve operational challenges, driving scalability through simplification, clarity, and standardization of process
• Lead the global commercial GxP change management process, holistically assessing impact of updates to a complex business process in collaboration with subject matter experts and owning change control activities, while fostering quality compliance across all initiatives
• Advance forward-thinking strategic projects in collaboration with the Disease Strategy Team, such as multi-year scaling roadmap and business process for next-generation manufacturing strategy  

Qualifications and Experience:

• Proven ability to manage multiple priorities in a fast-paced environment.
• Independent thinker with strong attention to detail and a collaborative mindset.
• Excellent project management skills to lead complex workstreams with multiple stakeholders and ability to work effectively across diverse functions and teams.
• Strong meeting facilitation and written and verbal communication skills.
• Experience with GxP process and change management is highly preferred.
• Familiarity with process analytics and reporting tools is a plus.

Why Join Us? At Vertex, you’ll be part of a team that is transforming the lives of patients through innovative therapies. We offer a dynamic and inclusive work environment where your contributions will make a meaningful impact.

How to Apply: If you are a driven professional with a passion for operational excellence and process optimization, we encourage you to apply. Please submit your resume and cover letter through our careers portal.

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as: 
1.    Hybrid: work remotely up to two days per week; or select
2.    On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. 

#LI-Hybrid
 

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]