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Senior Medical Director, Cardiology

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Job Description - Senior Medical Director, Cardiology

Serve as the lead U.S. cardiology expert within Medical Affairs, representing Alnylam across Tier 1 KOLs, amyloidosis centers, and national cardiology societies (AHA, ACC, HFSA). Lead executive-level scientific discussions to advance disease awareness, diagnostics, and treatment optimization. Build and sustain deep, trust-based relationships with key external experts to inform strategy and identify collaboration opportunities. Represent Alnylam Medical Affairs at major scientific meetings, symposia, and advisory boards. Partner with field medical leadership to shape KOL mapping, segmentation, and engagement strategy, ensuring alignment and execution excellence. Generate actionable scientific and clinical insights from external engagements and ensure integration into broader U.S. Medical Affairs insight and strategy processes. Operate as a senior individual contributor, leading scientific strategy and cross-functional partnerships without formal people-management responsibilities. MD or DO, Board-Certified Cardiologist required (Advanced Heart Failure or Amyloidosis specialization strongly preferred). 8-10+ years of combined clinical and medical affairs experience, with ≥3 years in an industry medical or strategy role. Deep understanding of the U.S. cardiology and rare disease landscape. Demonstrated success in engaging Tier 1 KOLs and external thought leaders at the national level. Strong cross-functional collaboration skills and ability to influence without authority. Exceptional communication, executive presence, and data storytelling skills. Ability to operate effectively in a fast-paced, high-accountability environment. Provide SME input into cross-functional initiatives, collaborating closely with Clinical Development, HEOR, Payer Medical, and Patient Advocacy. Support evidence generation and ISR strategies, including protocol input, data interpretation, and scientific dissemination. Deliver advanced cardiology and amyloidosis training for field medical teams to elevate scientific capabilities and ensure consistency in engagement. Ensure alignment of insights, field strategy, and scientific priorities across the Medical Affairs organization.
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