Senior Scientist

About Us

Monod Bio is a pioneer company in the design of de novo protein reagents for Life Sciences and Diagnostics. Our innovative design platform technology takes advantage of the most recent advances in deep learning computational protein engineering to create highly rapid and sensitive protein-based reagents and assays. Our visionary founding team and state-of-the-art technology and product development experience positions Monod Bio at the forefront of molecular reporter, binder and functional protein innovation, and we welcome exceptional individuals to join us in this journey.

About the Role

This is a hands-on, high-impact role for someone who thrives at the intersection of protein science, technical transfer, quality gates, and cross-functional execution. You will create systems that ensure the right data, the right material quality, and the right timelines reliably reach internal stakeholders and partners.

Key Responsibilities

• Design, implement, and continuously improve a scalable, end-to-end operational pipeline supporting internal programs and external partnerships


• Build and maintain systems to track project and batch status, dependencies, risks, and timelines, ensuring visibility and accountability across stakeholders


• Act as a coordination point between internal teams and external partners, ensuring alignment and reliable execution


• Define, establish, and enforce release criteria and quality gates for protein materials across development stages and handoffs


• Standardize data and deliverable packages (e.g., identity, purity, aggregation/SEC, yield, stability, binding performance), ensuring completeness and quality prior to downstream use or transfer


• Own external deliverables, including technical transfer packages, documentation, and Certificates of Analysis (CoAs).


• Proactively identify risks and issues, implement corrective actions, and prevent downstream failures through rigorous review and clear acceptance criteria


• Spend meaningful time in the lab to build deep familiarity with workflows, instrumentation, and common failure modes, while driving improvements in reliability, throughput, and reproducibility


• Troubleshoot protein production and characterization challenges (e.g., solubility, aggregation, purity, stability, assay or method issues), coordinating solutions with appropriate technical owners


• Oversee laboratory operations and instrumentation to ensure efficient, compliant, and high-quality day-to-day execution


• Establish and standardize protocols to drive consistency and operational excellence


• Manage inventory systems to ensure accurate tracking, availability, and organization of materials


• Lead and mentor technical associates, setting priorities, guiding daily activities, and ensuring strong performance and accountability


• Other duties and projects as needed or assigned

Required Skills, Qualifications & Attributes

• Advanced degree (PhD preferred) in biochemistry, protein engineering, molecular biology, chemical engineering, or related field; or equivalent industry experience


• A minimum of 5+ years of directly related experience including at least 2 years of experience supervising others


• Strong hands-on experience with recombinant protein production and purification


• Demonstrated experience with protein characterization tools and interpretation (e.g., SEC/SEC-MALS, SDS-PAGE, binding kinetics via BLI/SPR, thermal stability methods such as DSF/CD, or comparable assays)


• Proven ability to create and enforce quality standards, documentation practices, and reproducible workflows


• Comfortable operating in a fast-paced environment with multiple priorities and shifting timelines


• High ownership: identifies gaps, closes loops, and drives outcomes


• Strong scientific judgment with pragmatic execution bias


• Clear communicator who can translate technical findings into actionable plans and timelines.


• Collaborative, hands-on leader who raises the bar without creating bureaucracy.

Preferred Skills & Qualifications

• Experience managing tech transfer to external partners (e.g., contract manufacturing or service providers) and qualifying inbound material.


• Experience building R&D operational systems (templates, trackers, release packets, readiness checklists, cadence).


• Familiarity with modern R&D data systems (e.g., Benchling or similar ELN/LIMS tools).


• Experience supporting application-facing validation (assay fit-for-purpose, customer requirements translation).

Physical Environment and Key Requirements 

• Ability to perform work in both an office and laboratory environment. Will be in proximity to BSL2 labs.  Familiarity with biological and chemical hazard handling is desired.  Training and equipment will be provided, as necessary


• Office mobility and the ability to stand for periods of time as needed is required


• Mild odors from the manufacture of physical specimens and from laboratory work may be present. The environment has been tested, and proper engineering protections are in place.

We are proud to provide a generous benefits package and a healthy work culture:

• 100% company-paid medical, dental, life/AD&D, and vision insurance premiums for employees scheduled to work 25+ hours per week. 50% paid premiums for eligible dependents


• 4 weeks of PTO accrual per anniversary year plus 11 paid calendar year holidays


• Parental leave benefit


• State-of-the-art lab and office on bus line and near coffee shops, restaurants, and South Lake Union neighborhood


• Casual environment, friendly colleagues, and of course, excellent snacks in the kitchen!

Every position requires certain physical capabilities with the major ones for this role noted above. Monod Bio seeks to provide reasonable accommodations that enable individuals with disabilities to perform essential duties when possible. Equal employment opportunity is a fundamental principle at Monod Bio. We are committed to nondiscrimination in all business operations. We are proud to enjoy a respectful and inclusive work environment where everyone has the opportunity to thrive.