Senior Scientist, In Vivo Cardiovascular-Renal Disease

Description

The in vivo pharmacology group is seeking a highly motivated, early-career cardiovascular scientist to join our Cardiovascular-renal-metabolism (CRM) team in Ridgefield, CT. This role will focus on hands-on assessment of cardiovascular function in preclinical (rodent) models, with emphasis on invasive hemodynamics and/or small-animal echocardiography. This role offers the opportunity to lead from the bench initially and grow into scientific, project, and people leadership while advancing transformative therapies for cardio‑renal‑metabolic patients. 

Duties & Responsibilities

Cardiovascular in vivo expertise 

• Independently design, execute, and interpret cardiovascular functional studies in rodent models using 
  
  
  
  • Invasive hemodynamic techniques (ex: pressure-volume loops), and/or  
  
  
  • Rodent echocardiography (ex: systolic/diastolic function) 
  
  
  
  


• Maintain compliance with regulatory SOPs, IACUC procedures, and data integrity 


• This position requires moderate physical activity to complete work in the vivarium and laboratory. This position requires use of personal protective equipment (PPE) including respiratory, eye, hand, and foot protection.

Scientific and project contributions 

• Integrate cardiovascular expertise with chronic kidney disease pathology to advance drug discovery programs 


• Build and apply in vivo models and technical capabilities that reflect human disease pathology to inform program decisions  


• Communicate scientific results orally and in writing at internal and external meetings, leadership discussions, and global alignment meetings 


• Demonstrate emerging ability to lead drug discovery projects, influence others, and collaborate  cross-functionally 

Requirements

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  • Ph.D. Degree in Cardiovascular Disease, Pharmacology, Physiology, or equivalent experience in a related field; postdoctoral experience is preferred 
  
  
  • Demonstrated hands-on experience with rodent cardiovascular techniques, including invasive hemodynamics and/or echocardiography 
  
  
  • Proven ability design experiments, analyze complex data, troubleshoot in vivo pharmacology models, and translate findings into biological insight 
  
  
  • Experience in disease models relevant to heart failure, hypertension, and/or cardiorenal syndrome are preferred 
  
  
  • Ability to train, mentor, and collaborate with junior scientists effectively in a matrixed and culturally diverse environment 
  
  
  • Effective oral and written communication skills 
  
  
  • Willingness to support weekend in vivo work as needed 
  
  

  
  
  
  

Compensation:

 This position, Senior Scientist, offers a base salary typically between $140,000.00 and $222,000.00.  The position may be eligible for a role specific variable or performance based bonus and or other compensation elements. For an overview of our benefits please click here. 

Eligibility Requirements:

• Must be legally authorized to work in the United States without restriction.


• Must be willing to take a drug test and post-offer physical (if required).


• Must be 18 years of age or older.