Senior Scientist, Pharmacometrics

Apply simulation methods to support dose selection, trial design, and Go/No-Go decisions. Participate in the preparation of reports/abstracts/manuscripts for publications and regulatory documents. Education: Candidates with Ph.D. degree in pharmaceutics, pharmacokinetics, pharmacometrics, biostatistics, engineering disciples, and related quantitative fields. Experience: At least 2-3 years of post-doctoral experience in pharmaceutical industry or regulatory agency. Experience representing application of pharmacometrics in drug development and hands-on modeling experience. Strong proficiency in R programming, and in non-linear mixed effects modeling software like NONMEM. Good understanding of pharmacokinetic, pharmacodynamic principles and drug development Experience with programming clinical data sets. Strong written and oral communication skills and interpersonal skills. Strong statistical understanding of hierarchical modeling of longitudinal continuous and non-continuous data. Understanding of application of Bayesian methods. Application and development of system pharmacology models.