$145,000 - 175,000 yearly
Number of Applicants
:000+
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Verve is a clinical-stage genetic medicines company established with a mission to solve the global health epidemic of cardiovascular disease. Founded by world-leading experts in cardiovascular medicine, human genetics and gene-editing, Verve is pioneering a new approach to the care of cardiovascular disease, potentially transforming treatment from chronic management to single-course gene editing medicines. The company's initial three programs – VERVE-101, VERVE-102, and VERVE-201 – target genes that have been extensively validated as targets for lowering low-density lipoprotein cholesterol (LDL-C), a root cause of cardiovascular disease. VERVE-101 and VERVE-102 are designed to permanently turn off the PCSK9 gene in the liver and are being developed initially for heterozygous familial hypercholesterolemia (HeFH) and ultimately to treat atherosclerotic cardiovascular disease (ASCVD) patients not at goal on oral therapy. VERVE-201 is designed to permanently turn off the ANGPTL3 gene in the liver and is initially being developed for homozygous familial hypercholesterolemia (HoFH) and ultimately to treat patients with refractory hypercholesterolemia. In 2023, Verve was named a Top Place to Work by The Boston Globe for the third consecutive year. Verve is headquartered in Boston, Massachusetts.
Verve is seeking an experienced modeling senior scientist to join our team as we continue to advance gene editing medicines for cardiovascular disease into clinical development. The successful applicant will develop fit-for-purpose, quantitative systems pharmacology (QSP) models and support pharmacometric modeling across key gene editing programs. The modeler will collaborate closely with scientists across the non-clinical (in vivo pharmacology, bioanalysis, and toxicology) and clinical teams to provide feedback on interpretation of experimental data and on study design to advance the understanding of gene editing drugs. In addition, and in collaboration with expert consultants, they will analyze data obtained from trial participants treated with Verve gene editing products. The individual will help develop the overall strategy for quantitative systems pharmacology and support effective communication with health authorities.
Job ResponsibilitiesThe targeted salary range for this position is $145,000 - $175,000 per year. Verve is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Verve's compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.
Verve Therapeutics is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.
Recruitment & Staffing AgenciesVerve Therapeutics does not accept agency resumes unless contacted directly by internal Verve Talent Acquisition. Please do not forward resumes to Verve employees or any other company location; Verve Therapeutics is not responsible for any fees related to unsolicited resumes.
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